Gene
ccka
- ID
- ZDB-GENE-100922-79
- Name
- cholecystokinin a
- Symbol
- ccka Nomenclature History
- Previous Names
-
- CCK8 (1)
- cck
- si:ch73-138e9.1
- Type
- protein_coding_gene
- Location
- Chr: 16 Mapping Details/Browsers
- Description
- Predicted to enable neuropeptide hormone activity. Predicted to be involved in digestion. Predicted to be located in extracellular region. Predicted to be active in axon and extracellular space. Is expressed in digestive system; gut; intestine; and preoptic area. Human ortholog(s) of this gene implicated in alcohol dependence and nicotine dependence. Orthologous to human CCK (cholecystokinin).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 9 figures from 8 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
No data available
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Cholecystokinin-like | Gastrin/cholecystokinin, conserved site | Gastrin/cholecystokinin peptide hormone |
|---|---|---|---|---|---|
| UniProtKB:E9QEB3 | InterPro | 123 |
1 - 1 of 1
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Zebrafish Nomenclature Committee (2025) Nomenclature Data Curation (2025). Nomenclature Committee Submission.
- Hui, J.C.M., Du, P., Webb, S.E., Liu, J.Y.H., Ngan, M.P., Lu, Z., Ng, H.S.H., Yang, L., Khalid, A., Liu, L., Li, Z., Deng, Y., Cui, D., Rudd, J.A. (2024) Imaging analytical technique to assess gastrointestinal motility in vivo using zebrafish larvae with diabetes mellitus-like traits. PLoS One. 19:e0314515e0314515
- Spikol, E.D., Cheng, J., Macurak, M., Subedi, A., Halpern, M.E. (2024) Genetically defined nucleus incertus neurons differ in connectivity and function. eLIFE. 12:
- Zebrafish Nomenclature Committee (2024) Nomenclature Data Curation (2024). Nomenclature Committee Submission.
- Zhu, X., Zhang, D., Wang, Y., Wang, C., Liu, X., Niu, Y. (2024) Study on the signaling pathways involved in the anti-hyperglycemic effect of raspberry ketone on zebrafish using integrative transcriptome and metabolome analyses. Food & function. 15(18):9457-9470
- Dai, X., Pradhan, A., Liu, J., Liu, R., Zhai, G., Zhou, L., Dai, J., Shao, F., Yuan, Z., Wang, Z., Yin, Z. (2023) Zebrafish gonad mutant models reveal neuroendocrine mechanisms of brain sexual dimorphism and male mating behaviors of different brain regions. Biology of sex differences. 14:5353
- Ahi, E.P., Brunel, M., Tsakoumis, E., Chen, J., Schmitz, M. (2022) Appetite regulating genes in zebrafish gut; a gene expression study. PLoS One. 17:e0255201
- de Alba, G., Carrillo, S., Sánchez-Vázquez, F.J., López-Olmeda, J.F. (2022) Combined blue light and daily thermocycles enhance zebrafish growth and development. Journal of experimental zoology. Part A, Ecological and integrative physiology. 337(5):501-515
- Athapaththu, A.M.G.K., Molagoda, I.M.N., Jayasooriya, R.G.P.T., Choi, Y.H., Jeon, Y.J., Park, J.H., Lee, B.J., Kim, G.Y. (2021) Gamma-Aminobutyric Acid (GABA) Promotes Growth in Zebrafish Larvae by Inducing IGF-1 Expression via GABAA and GABAB Receptors. International Journal of Molecular Sciences. 22(20):
- Del Vecchio, G., Murashita, K., Verri, T., Gomes, A.S., Rønnestad, I. (2021) Leptin receptor-deficient (knockout) zebrafish: effects on nutrient acquisition. General and comparative endocrinology. 310:113832
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