Gene

armc9

ID

ZDB-GENE-100922-67

Name

armadillo repeat containing 9

Symbol

armc9 Nomenclature History

Previous Names

si:ch1073-404h7.1

Type

protein_coding_gene

Location

Chr: 22 Mapping Details/Browsers

Description

Acts upstream of or within cilium assembly. Predicted to be active in centriole; ciliary basal body; and ciliary tip. Is expressed in central nervous system and retina. Used to study Joubert syndrome.

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

2 figures from Van De Weghe et al., 2017

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 3 figures from 2 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With armc9 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
Joubert syndrome 30	Alliance	Joubert syndrome 30	617622

Associated With armc9 Via Experimental Models

Human Disease	Fish	Conditions	Citations
Joubert syndrome	armc9^zh502/zh502	standard conditions	Latour et al., 2020
Joubert syndrome	armc9^zh503/zh503	standard conditions	Latour et al., 2020
Joubert syndrome	armc9^zh504/zh504	standard conditions	Latour et al., 2020
Joubert syndrome	armc9^zh505/zh505	standard conditions	Latour et al., 2020

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR006594	LIS1 homology motif
Conserved_site	IPR048957	ARMC9, LIS1 homology motif
Domain	IPR048959	LisH domain-containing protein ARMC9, ARM repeat domain
Domain	IPR056327	ARMC9, CTLH-like domain
Family	IPR040369	LisH domain-containing protein ARMC9
Homologous_superfamily	IPR011989	Armadillo-like helical
Homologous_superfamily	IPR016024	Armadillo-type fold

Domain Details Per Protein

Protein	Additional Resources	Length	Armadillo-like helical	Armadillo-type fold	ARMC9, CTLH-like domain	ARMC9, LIS1 homology motif	LIS1 homology motif	LisH domain-containing protein ARMC9	LisH domain-containing protein ARMC9, ARM repeat domain
UniProtKB:A0AB32TC76	InterPro	829

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Annotation Method	Has Havana Data	Length (nt)	Analysis
mRNA	armc9-202 (1) Ensembl	Ensembl		1,965 nt	Select Tool ZFIN BLAST
ncRNA	armc9-002 (1) Ensembl	Ensembl		537 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations