Gene

inpp5d

ID
ZDB-GENE-100922-30
Name
inositol polyphosphate-5-phosphatase D
Symbol
inpp5d Nomenclature History
Previous Names
  • SHIP1 (1)
  • si:ch73-194h10.1
Type
protein_coding_gene
Location
Chr: 6 Mapping Details/Browsers
Description
Predicted to enable phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity. Acts upstream of or within negative regulation of neutrophil chemotaxis. Predicted to be located in cytoplasm; cytoskeleton; and membrane. Predicted to be active in cytosol. Orthologous to human INPP5D (inositol polyphosphate-5-phosphatase D).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Lam et al., 2012
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Allele Type Localization Consequence Mutagen Supplier
sa18179Allele with one point mutationUnknownPremature StopENU
Zebrafish International Resource Center (ZIRC) (order this)
European Zebrafish Resource Center (EZRC) (order this)
sa40704Allele with one point mutationUnknownPremature StopENU
Zebrafish International Resource Center (ZIRC) (order this)
European Zebrafish Resource Center (EZRC) (order this)
sa40705Allele with one point mutationUnknownPremature StopENU
Zebrafish International Resource Center (ZIRC) (order this)
European Zebrafish Resource Center (EZRC) (order this)
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Sequence Targeting Reagents
Targeting Reagent Created Alleles Citations
MO1-inpp5dN/ALam et al., 2012
MO2-inpp5dN/ALam et al., 2012
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Human Disease
Associated With inpp5d Human Ortholog
No data available
Associated With inpp5d Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000300 Inositol polyphosphate-related phosphatase
Domain IPR000980 SH2 domain
Homologous_superfamily IPR036691 Endonuclease/exonuclease/phosphatase superfamily
Homologous_superfamily IPR036860 SH2 domain superfamily
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Domain Details Per Protein
Protein Additional Resources Length Endonuclease/exonuclease/phosphatase superfamily Inositol polyphosphate-related phosphatase SH2 domain SH2 domain superfamily
UniProtKB:A0A8M9Q0J1 InterPro 1108
UniProtKB:A0A8M9P974 InterPro 1108
UniProtKB:A0A8M1QLP5 InterPro 1108
UniProtKB:A0AB32THI2 InterPro 1055
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Transcripts
Genome Browsers
Genome Build: GRCz11Chromosome: 6
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA inpp5d-201 (1)
Ensembl
Ensembl 3,249 nt
ZFIN BLAST
mRNA inpp5d-204 (1)
Ensembl
Ensembl 2,826 nt
ZFIN BLAST
mRNA inpp5d-205 (1)
Ensembl
Ensembl 3,147 nt
ZFIN BLAST
ncRNA inpp5d-002 (1)
Ensembl
Ensembl 414 nt
ZFIN BLAST
ncRNA inpp5d-003 (1)
Ensembl
Ensembl 796 nt
ZFIN BLAST
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Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
No data available
Marker Relationships
Relationship Marker Type Marker Accession Numbers Citations
Contained inBACCH73-194H10ZFIN Curated Data
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Sequences
Type Accession # Sequence Length (nt/aa) Analysis
RNARefSeq:XM_068219213 (1)3533 nt
ZFIN BLASTNCBI BLASTEnsemblUCSC BLAT
GenomicGenBank:BX005335 (1)211094 nt
MegaBLAST
PolypeptideUniProtKB:A0A8M1QLP5 (1)1108 aa
ZFIN BLASTSIB BLASTEnsembl Protein Blast
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Species Symbol Chromosome Accession # Evidence
HumanINPP5D2
Amino acid sequence comparison (1)
Citations
TSV
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