Gene
ttll5
- ID
- ZDB-GENE-100922-236
- Name
- tubulin tyrosine ligase-like family, member 5
- Symbol
- ttll5 Nomenclature History
- Previous Names
-
- si:ch1073-297m1.2 (1)
- Type
- protein_coding_gene
- Location
- Chr: 17 Mapping Details/Browsers
- Description
- Predicted to enable tubulin binding activity and tubulin-glutamic acid ligase activity. Predicted to be involved in microtubule cytoskeleton organization and protein polyglutamylation. Predicted to act upstream of or within protein modification process. Predicted to be active in cilium. Human ortholog(s) of this gene implicated in cone-rod dystrophy 19. Orthologous to human TTLL5 (tubulin tyrosine ligase like 5).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| cone-rod dystrophy 19 | Alliance | Cone-rod dystrophy 19 | 615860 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Family | IPR004344 | Tubulin-tyrosine ligase/Tubulin polyglutamylase |
Domain Details Per Protein
| Protein | Length | Tubulin-tyrosine ligase/Tubulin polyglutamylase |
|---|---|---|
|
UniProtKB:A0A140LH35
|
1190 | |
|
UniProtKB:A0A8M1PZV3
|
1151 |
Interactions and Pathways
No data available
Plasmids
No data available