Gene

trak1a

ID

ZDB-GENE-100922-182

Name

trafficking protein, kinesin binding 1a

Symbol

trak1a Nomenclature History

Previous Names

trak1
si:ch73-138e9.2

Type

protein_coding_gene

Location

Chr: 16 Mapping Details/Browsers

Description

Predicted to enable GABA receptor binding activity and myosin binding activity. Predicted to be involved in several processes, including endosome to lysosome transport; mitochondrion distribution; and organelle transport along microtubule. Predicted to be located in early endosome and mitochondrion. Predicted to be active in dendrite. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 68. Orthologous to human TRAK1 (trafficking kinesin protein 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With trak1a Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
developmental and epileptic encephalopathy 68	Alliance	Developmental and epileptic encephalopathy 68	618201

Associated With trak1a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR006933	HAP1, N-terminal
Domain	IPR022154	Trafficking kinesin-binding protein, C-terminal
Family	IPR051946	Intracellular Trafficking Regulator

Domain Details Per Protein

Protein	Length	HAP1, N-terminal	Intracellular Trafficking Regulator	Trafficking kinesin-binding protein, C-terminal
UniProtKB:A0A8M3AIV7 InterPro	920
UniProtKB:E9QJ68 InterPro	860
UniProtKB:A0A8M3AT45 InterPro	890
UniProtKB:A0A8M3B1F5 InterPro	935
UniProtKB:A0A8M3B1F9 InterPro	647
UniProtKB:A0A8M9PMV3 InterPro	704

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	trak1a-201 (1) Ensembl	Ensembl	1,821 nt	Select Tool ZFIN BLAST
mRNA	trak1a-202 (1) Ensembl	Ensembl	5,009 nt	Select Tool ZFIN BLAST
ncRNA	trak1-002 (1) Ensembl	Ensembl	424 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations