Gene

fndc7b

ID

ZDB-GENE-100922-114

Name

fibronectin type III domain containing 7b

Symbol

fndc7b Nomenclature History

Previous Names

si:ch1073-154c4.1

Type

protein_coding_gene

Location

Chr: 23 Mapping Details/Browsers

Description

None

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Allele	Type	Localization	Consequence	Mutagen	Supplier
sa8958	Allele with one point mutation	Unknown	Premature Stop	ENU	European Zebrafish Resource Center (EZRC) (order this) Zebrafish International Resource Center (ZIRC) (order this)
sa9051	Allele with one point mutation	Unknown	Unknown	ENU	Zebrafish International Resource Center (ZIRC) (order this)
sa10526	Allele with one point mutation	Unknown	Splice Site	ENU	European Zebrafish Resource Center (EZRC) (order this) Zebrafish International Resource Center (ZIRC) (order this)
sa10770	Allele with one point mutation	Unknown	Premature Stop	ENU	European Zebrafish Resource Center (EZRC) (order this) Zebrafish International Resource Center (ZIRC) (order this)
sa12031	Allele with one point mutation	Unknown	Splice Site	ENU	European Zebrafish Resource Center (EZRC) (order this)
sa15780	Allele with one point mutation	Unknown	Premature Stop	ENU	European Zebrafish Resource Center (EZRC) (order this) Zebrafish International Resource Center (ZIRC) (order this)
sa24237	Allele with one point mutation	Unknown	Splice Site	ENU	Zebrafish International Resource Center (ZIRC) (order this) European Zebrafish Resource Center (EZRC) (order this)
sa24238	Allele with one point mutation	Unknown	Splice Site	ENU	Zebrafish International Resource Center (ZIRC) (order this) European Zebrafish Resource Center (EZRC) (order this)
sa31077	Allele with one point mutation	Unknown	Unknown	ENU	Zebrafish International Resource Center (ZIRC) (order this)
sa37588	Allele with one point mutation	Unknown	Premature Stop	ENU	Zebrafish International Resource Center (ZIRC) (order this) European Zebrafish Resource Center (EZRC) (order this)

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Sequence Targeting Reagents

No data available

Human Disease

Associated With fndc7b Human Ortholog

No data available

Associated With fndc7b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR003961	Fibronectin type III
Domain	IPR015373	Interferon/interleukin receptor domain
Homologous_superfamily	IPR013783	Immunoglobulin-like fold
Homologous_superfamily	IPR036116	Fibronectin type III superfamily

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Domain Details Per Protein

Protein	Additional Resources	Length	Fibronectin type III	Fibronectin type III superfamily	Immunoglobulin-like fold	Interferon/interleukin receptor domain
UniProtKB:A0A8M1RHU1	InterPro	4712

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Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Genome Build: GRCz11Chromosome: 23

Type	Name	Annotation Method	Has Havana Data	Length (nt)	Analysis
mRNA	fndc7b-201 (1) Ensembl	Ensembl		639 nt	Select Tool ZFIN BLAST
mRNA	fndc7b-202 (1) Ensembl	Ensembl		929 nt	Select Tool ZFIN BLAST

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Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

No data available

Marker Relationships

Relationship	Marker Type	Marker	Accession Numbers	Citations
Contained in	Fosmid	CH1073-154C4	CU633850	ZFIN Curated Data

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Sequences

Type	Accession #	Length (nt/aa)	Analysis
RNA	RefSeq:XM_002665313 (1)	14464 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
Genomic	GenBank:CU633850 (1)	37149 nt	Select Tool MegaBLAST Ensembl
Polypeptide	UniProtKB:A0A8M1RHU1 (1)	4712 aa	Select Tool ZFIN BLAST SIB BLAST Ensembl Protein Blast

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Species	Symbol	Chromosome	Accession #	Evidence
Human	FNDC7	1	Ensembl:ENSG00000143107 Gene:163479 HGNC:26668	Conserved genome location (synteny) (1) Amino acid sequence comparison (1)
Mouse	Fndc7	3	Ensembl:ENSMUSG00000045326 Gene:320181 MGI:2443535	Amino acid sequence comparison (1) Conserved genome location (synteny) (1)

Citations

Include unpublished citations

Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549

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