Gene
fkbp10a
- ID
- ZDB-GENE-100921-75
- Name
- FKBP prolyl isomerase 10a
- Symbol
- fkbp10a Nomenclature History
- Previous Names
-
- si:ch73-218h2.1
- Type
- protein_coding_gene
- Location
- Chr: 19 Mapping Details/Browsers
- Description
- Predicted to enable peptidyl-prolyl cis-trans isomerase activity. Predicted to be involved in protein folding. Predicted to be active in endoplasmic reticulum. Human ortholog(s) of this gene implicated in osteogenesis imperfecta type 11. Orthologous to human FKBP10 (FKBP prolyl isomerase 10).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Bruck syndrome | Alliance | Bruck syndrome 1 | 259450 |
| osteogenesis imperfecta type 11 | Alliance | Osteogenesis imperfecta, type XI | 610968 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Binding_site | IPR018247 | EF-Hand 1, calcium-binding site |
| Domain | IPR001179 | FKBP-type peptidyl-prolyl cis-trans isomerase domain |
| Domain | IPR002048 | EF-hand domain |
| Family | IPR051989 | FK506-binding protein-like isomerase |
| Homologous_superfamily | IPR011992 | EF-hand domain pair |
| Homologous_superfamily | IPR046357 | Peptidyl-prolyl cis-trans isomerase domain superfamily |
Domain Details Per Protein
| Protein | Length | EF-Hand 1, calcium-binding site | EF-hand domain | EF-hand domain pair | FK506-binding protein-like isomerase | FKBP-type peptidyl-prolyl cis-trans isomerase domain | Peptidyl-prolyl cis-trans isomerase domain superfamily |
|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M2B6F8
|
510 | ||||||
|
UniProtKB:A0A8M2B6A9
|
352 | ||||||
|
UniProtKB:A0A8M9PBG3
|
563 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
fkbp10a-201
(1)
|
Ensembl | 1,978 nt |
Interactions and Pathways
No data available
Plasmids
No data available