Gene
frmd4bb
- ID
- ZDB-GENE-100921-74
- Name
- FERM domain containing 4Bb
- Symbol
- frmd4bb Nomenclature History
- Previous Names
-
- si:ch73-205c16.1
- Type
- protein_coding_gene
- Location
- Chr: 23 Mapping Details/Browsers
- Description
- Predicted to be involved in developmental process. Predicted to act upstream of or within establishment of epithelial cell polarity. Predicted to be located in cytoskeleton and membrane. Predicted to be active in adherens junction and bicellular tight junction. Is expressed in female organism. Orthologous to human FRMD4B (FERM domain containing 4B).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Newman et al., 2019
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR019747 | FERM conserved site |
| Domain | IPR000299 | FERM domain |
| Domain | IPR018979 | FERM, N-terminal |
| Domain | IPR018980 | FERM, C-terminal PH-like domain |
| Domain | IPR019748 | FERM central domain |
| Domain | IPR019749 | Band 4.1 domain |
| Domain | IPR021774 | Cytohesin Ubiquitin Protein Inducing Domain |
| Domain | IPR041785 | FRMD4A/B, FERM domain C-lobe |
| Family | IPR047176 | FERM domain-containing protein 4A/B |
| Homologous_superfamily | IPR011993 | PH-like domain superfamily |
| Homologous_superfamily | IPR014352 | FERM/acyl-CoA-binding protein superfamily |
| Homologous_superfamily | IPR029071 | Ubiquitin-like domain superfamily |
| Homologous_superfamily | IPR035963 | FERM superfamily, second domain |
Domain Details Per Protein
| Protein | Additional Resources | Length | Band 4.1 domain | Cytohesin Ubiquitin Protein Inducing Domain | FERM/acyl-CoA-binding protein superfamily | FERM central domain | FERM conserved site | FERM, C-terminal PH-like domain | FERM domain | FERM domain-containing protein 4A/B | FERM, N-terminal | FERM superfamily, second domain | FRMD4A/B, FERM domain C-lobe | PH-like domain superfamily | Ubiquitin-like domain superfamily |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M3B5U7 | InterPro | 972 | |||||||||||||
| UniProtKB:A0A8M3AV01 | InterPro | 1053 | |||||||||||||
| UniProtKB:A0A8M9PKW3 | InterPro | 678 | |||||||||||||
| UniProtKB:A0A8M3AMJ5 | InterPro | 1034 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
frmd4bb-201
(1)
|
Ensembl | 3,000 nt | ||
| mRNA |
frmd4bb-202
(1)
|
Ensembl | 2,819 nt |
Interactions and Pathways
No data available
Plasmids
No data available