Gene

frmd4bb

ID

ZDB-GENE-100921-74

Name

FERM domain containing 4Bb

Symbol

frmd4bb Nomenclature History

Previous Names

si:ch73-205c16.1

Type

protein_coding_gene

Location

Chr: 23 Mapping Details/Browsers

Description

Predicted to localize to adherens junction and bicellular tight junction. Is expressed in female organism. Orthologous to human FRMD4B (FERM domain containing 4B).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Newman et al., 2019

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With frmd4bb Human Ortholog

No data available

Associated With frmd4bb Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR019747	FERM conserved site
Domain	IPR000299	FERM domain
Domain	IPR018979	FERM, N-terminal
Domain	IPR018980	FERM, C-terminal PH-like domain
Domain	IPR019748	FERM central domain
Domain	IPR019749	Band 4.1 domain
Domain	IPR021774	Cytohesin Ubiquitin Protein Inducing Domain
Domain	IPR041785	FRMD4A/B, FERM domain C-lobe
Family	IPR047176	FERM domain-containing protein 4A/B
Homologous_superfamily	IPR011993	PH-like domain superfamily
Homologous_superfamily	IPR014352	FERM/acyl-CoA-binding protein superfamily
Homologous_superfamily	IPR029071	Ubiquitin-like domain superfamily
Homologous_superfamily	IPR035963	FERM superfamily, second domain

Domain Details Per Protein

Protein	Length	Band 4.1 domain	Cytohesin Ubiquitin Protein Inducing Domain	FERM/acyl-CoA-binding protein superfamily	FERM central domain	FERM conserved site	FERM, C-terminal PH-like domain	FERM domain	FERM domain-containing protein 4A/B	FERM, N-terminal	FERM superfamily, second domain	FRMD4A/B, FERM domain C-lobe	PH-like domain superfamily	Ubiquitin-like domain superfamily
UniProtKB:A0A8M3B5U7 InterPro	972
UniProtKB:A0A8M3AV01 InterPro	1053
UniProtKB:A0A8M9PKW3 InterPro	678
UniProtKB:A0A8M3AMJ5 InterPro	1034

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Annotation Method	Has Havana Data	Length (nt)	Analysis
mRNA	frmd4bb-201 (1) Ensembl	Ensembl		3,000 nt	Select Tool ZFIN BLAST
mRNA	frmd4bb-202 (1) Ensembl	Ensembl		2,819 nt	Select Tool

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations