Gene

ptpn23a

ID

ZDB-GENE-100921-24

Name

protein tyrosine phosphatase, non-receptor type 23, a

Symbol

ptpn23a Nomenclature History

Previous Names

si:dkey-201i6.7

Type

protein_coding_gene

Location

Chr: 16 Mapping Details/Browsers

Description

Predicted to have protein tyrosine phosphatase activity. Predicted to be involved in protein dephosphorylation. Orthologous to human PTPN23 (protein tyrosine phosphatase non-receptor type 23).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from van Eekelen et al., 2010

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With ptpn23a Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		Neurodevelopmental disorder and structural brain anomalies with or without seizures and spasticity	618890

Associated With ptpn23a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Active_site	IPR016130	Protein-tyrosine phosphatase, active site
Domain	IPR000242	Tyrosine-specific protein phosphatase, PTPase domain
Domain	IPR000387	Tyrosine-specific protein phosphatases domain
Domain	IPR003595	Protein-tyrosine phosphatase, catalytic
Domain	IPR004328	BRO1 domain
Domain	IPR016103	ProQ/FinO domain
Domain	IPR025304	ALIX V-shaped domain
Homologous_superfamily	IPR029021	Protein-tyrosine phosphatase-like
Homologous_superfamily	IPR038499	BRO1 domain superfamily