ZFIN is now using GRCz12tu for Genomic Data
Gene
aatkb
- ID
- ZDB-GENE-100812-6
- Name
- apoptosis-associated tyrosine kinase b
- Symbol
- aatkb Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 12 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable protein tyrosine kinase activity. Predicted to be involved in brain development and neuron apoptotic process. Predicted to be located in cytoplasm; endomembrane system; and membrane. Orthologous to human AATK (apoptosis associated tyrosine kinase).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Challa et al., 2013
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Active_site | IPR008266 | Tyrosine-protein kinase, active site |
| Binding_site | IPR017441 | Protein kinase, ATP binding site |
| Domain | IPR000719 | Protein kinase domain |
| Domain | IPR001245 | Serine-threonine/tyrosine-protein kinase, catalytic domain |
| Domain | IPR020635 | Tyrosine-protein kinase, catalytic domain |
| Homologous_superfamily | IPR011009 | Protein kinase-like domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | Protein kinase, ATP binding site | Protein kinase domain | Protein kinase-like domain superfamily | Serine-threonine/tyrosine-protein kinase, catalytic domain | Tyrosine-protein kinase, active site | Tyrosine-protein kinase, catalytic domain |
|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M9QET8 | InterPro | 1572 | ||||||
| UniProtKB:A0A8N7TCQ8 | InterPro | 1657 | ||||||
| UniProtKB:A0A8M9Q963 | InterPro | 1657 | ||||||
| UniProtKB:A0A8M2B2G2 | InterPro | 1572 | ||||||
| UniProtKB:A0A8M3BEB4 | InterPro | 1482 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers