ZFIN is now using GRCz12tu for Genomic Data
Gene

mcf2l2

ID
ZDB-GENE-100812-1
Name
MCF.2 cell line derived transforming sequence-like 2
Symbol
mcf2l2 Nomenclature History
Previous Names
None
Type
protein_coding_gene
Location
Chr: 11 Mapping Details/Browsers
Genome Assembly
GRCz12tu
Annotation Status
Current
Description
Predicted to enable guanyl-nucleotide exchange factor activity. Predicted to be active in cytoplasm. Orthologous to human MCF2L2 (MCF.2 cell line derived transforming sequence-like 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With mcf2l2 Human Ortholog
No data available
Associated With mcf2l2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR001331 Guanine-nucleotide dissociation stimulator, CDC24, conserved site
Domain IPR000219 Dbl homology domain
Domain IPR001251 CRAL-TRIO lipid binding domain
Domain IPR001452 SH3 domain
Domain IPR001849 Pleckstrin homology domain
Domain IPR035532 DBS, SH3 domain
Domain IPR035534 DBS, PH domain
Domain IPR055251 SOS1/NGEF-like, PH domain
Domain IPR056466 Guanine nucleotide exchange factor DBS-like, spectrin-like
Family IPR051336 Rho GTPase-activating Guanine Nucleotide Exchange Factors
Homologous_superfamily IPR011993 PH-like domain superfamily
Homologous_superfamily IPR035899 Dbl homology (DH) domain superfamily
Homologous_superfamily IPR036028 SH3-like domain superfamily
Homologous_superfamily IPR036865 CRAL-TRIO lipid binding domain superfamily
Repeat IPR018159 Spectrin/alpha-actinin
Domain Details Per Protein
Protein Additional Resources Length CRAL-TRIO lipid binding domain CRAL-TRIO lipid binding domain superfamily Dbl homology (DH) domain superfamily Dbl homology domain DBS, PH domain DBS, SH3 domain Guanine-nucleotide dissociation stimulator, CDC24, conserved site Guanine nucleotide exchange factor DBS-like, spectrin-like PH-like domain superfamily Pleckstrin homology domain Rho GTPase-activating Guanine Nucleotide Exchange Factors SH3 domain SH3-like domain superfamily SOS1/NGEF-like, PH domain Spectrin/alpha-actinin
UniProtKB:A0A8M9QLV2 InterPro 1160
UniProtKB:A0A8M9QHY0 InterPro 1283
UniProtKB:A0A8M3AXG6 InterPro 1259
UniProtKB:A0A8M9Q7I6 InterPro 1274
UniProtKB:A0A8M3AXE9 InterPro 1229
UniProtKB:A0A8M9QDF3 InterPro 1221
UniProtKB:A0A8M9PV88 InterPro 1282
UniProtKB:A0A8M9QLU9 InterPro 1284
UniProtKB:A0A8M3BDJ3 InterPro 1237
UniProtKB:A0AB32TX70 InterPro 1072
UniProtKB:A0AC58GRY3 InterPro 1284
UniProtKB:A0AC58GRY5 InterPro 1272
UniProtKB:A0AC58GRY6 InterPro 1218
UniProtKB:A0AC58GRY7 InterPro 1257
UniProtKB:A0AC58GRY8 InterPro 1249
UniProtKB:A0AC58GRY9 InterPro 1235
UniProtKB:A0AC58GRZ0 InterPro 1229
UniProtKB:A0AC58GRZ2 InterPro 1221
UniProtKB:A0AC58GRZ3 InterPro 1247
UniProtKB:A0AC58GRZ5 InterPro 1282
UniProtKB:A0AC58GRZ6 InterPro 1217
UniProtKB:A0AC58GRZ7 InterPro 1211
UniProtKB:A0AC58GRZ8 InterPro 1217
UniProtKB:A0AC58GRZ9 InterPro 1216
UniProtKB:A0AC58GS00 InterPro 1154
UniProtKB:A0AC58GS01 InterPro 1184
UniProtKB:A0AC58GS02 InterPro 1163
UniProtKB:A0AC58GS04 InterPro 1274
UniProtKB:A0AC58GS05 InterPro 1160
UniProtKB:A0AC58GS06 InterPro 1134
UniProtKB:A0AC58GS07 InterPro 1151
UniProtKB:A0AC58GS08 InterPro 1135
UniProtKB:A0AC58GS09 InterPro 1133
UniProtKB:A0AC58GS10 InterPro 1186
UniProtKB:A0AC58GS11 InterPro 1132
UniProtKB:A0AC58GS12 InterPro 1113
UniProtKB:A0AC58GS13 InterPro 1196
UniProtKB:A0AC58GS14 InterPro 1132
UniProtKB:A0AC58GS15 InterPro 1194
UniProtKB:A0AC58GS16 InterPro 1095
UniProtKB:A0AC58GS17 InterPro 998
UniProtKB:A0AC58GS19 InterPro 1096
UniProtKB:A0AC58GS20 InterPro 1098
UniProtKB:A0AC58GS21 InterPro 1069
UniProtKB:A0AC58GS22 InterPro 1078
UniProtKB:A0AC58GS23 InterPro 1097
UniProtKB:A0AC58GS24 InterPro 1071
UniProtKB:A0AC58GS25 InterPro 1070
UniProtKB:A0AC58GS26 InterPro 1048
UniProtKB:A0AC58GS27 InterPro 1050
UniProtKB:A0AC58GS28 InterPro 1111
UniProtKB:A0AC58GS29 InterPro 1049
UniProtKB:A0AC58GS30 InterPro 1100
UniProtKB:A0AC58GS32 InterPro 976
UniProtKB:A0AC58GS34 InterPro 995
UniProtKB:A0AC58GS43 InterPro 997
UniProtKB:A0AC58GS46 InterPro 996
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA mcf2l2-201 (1)
Ensembl
Ensembl 4,252 nt
ZFIN BLAST
mRNA mcf2l2-202 (1)
Ensembl
Ensembl 6,479 nt
ZFIN BLAST
mRNA mcf2l2-203 (1)
Ensembl
Ensembl 4,333 nt
ZFIN BLAST
mRNA mcf2l2-204 (1)
Ensembl
Ensembl 3,841 nt
ZFIN BLAST
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Genome Browsers
Orthology
Comparative Orthology
Alliance
Citations
Your Input Welcome
We welcome your input and comments. Please use this form to recommend updates to the information in ZFIN. We appreciate as much detail as possible and references as appropriate. We will review your comments promptly.
Please check the highlighted fields and try again.
Thank you for submitting comments. Your input has been emailed to ZFIN curators who may contact you if additional information is required.
Oops. Something went wrong. Please try again later.