Gene
mcf2l2
- ID
- ZDB-GENE-100812-1
- Name
- MCF.2 cell line derived transforming sequence-like 2
- Symbol
- mcf2l2 Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 11 Mapping Details/Browsers
- Description
- Predicted to enable guanyl-nucleotide exchange factor activity. Predicted to act upstream of or within intracellular signal transduction. Predicted to be active in cytoplasm. Orthologous to human MCF2L2 (MCF.2 cell line derived transforming sequence-like 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR001331 | Guanine-nucleotide dissociation stimulator, CDC24, conserved site |
| Domain | IPR001251 | CRAL-TRIO lipid binding domain |
| Domain | IPR001452 | SH3 domain |
| Domain | IPR001849 | Pleckstrin homology domain |
| Domain | IPR035532 | DBS, SH3 domain |
| Domain | IPR035534 | DBS, PH domain |
| Domain | IPR055251 | SOS1/NGEF-like, PH domain |
| Family | IPR051336 | Rho GTPase-activating Guanine Nucleotide Exchange Factors |
| Homologous_superfamily | IPR011993 | PH-like domain superfamily |
| Homologous_superfamily | IPR035899 | Dbl homology (DH) domain superfamily |
| Homologous_superfamily | IPR036028 | SH3-like domain superfamily |
| Homologous_superfamily | IPR036865 | CRAL-TRIO lipid binding domain superfamily |
| Repeat | IPR018159 | Spectrin/alpha-actinin |
Domain Details Per Protein
| Protein | Additional Resources | Length | CRAL-TRIO lipid binding domain | CRAL-TRIO lipid binding domain superfamily | Dbl homology (DH) domain superfamily | DBS, PH domain | DBS, SH3 domain | Guanine-nucleotide dissociation stimulator, CDC24, conserved site | PH-like domain superfamily | Pleckstrin homology domain | Rho GTPase-activating Guanine Nucleotide Exchange Factors | SH3 domain | SH3-like domain superfamily | SOS1/NGEF-like, PH domain | Spectrin/alpha-actinin |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M9QLV2 | InterPro | 1160 | |||||||||||||
| UniProtKB:A0A8M9QHY0 | InterPro | 1283 | |||||||||||||
| UniProtKB:A0A8M3AXG6 | InterPro | 1259 | |||||||||||||
| UniProtKB:A0A8M9Q7I6 | InterPro | 1274 | |||||||||||||
| UniProtKB:A0A8M3AXE9 | InterPro | 1229 | |||||||||||||
| UniProtKB:A0A8M9QDF3 | InterPro | 1221 | |||||||||||||
| UniProtKB:A0A8M9PV88 | InterPro | 1282 | |||||||||||||
| UniProtKB:A0A8M9QLU9 | InterPro | 1284 | |||||||||||||
| UniProtKB:A0A8M3BDJ3 | InterPro | 1237 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
mcf2l2-201
(1)
|
Ensembl | 4,252 nt | ||
| mRNA |
mcf2l2-202
(1)
|
Ensembl | 6,479 nt | ||
| mRNA |
mcf2l2-203
(1)
|
Ensembl | 4,333 nt | ||
| mRNA |
mcf2l2-204
(1)
|
Ensembl | 3,841 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Comparative Orthology
- Alliance