Gene
adcy1b
- ID
- ZDB-GENE-100805-1
- Name
- adenylate cyclase 1b
- Symbol
- adcy1b Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 2 Mapping Details/Browsers
- Description
- Predicted to have adenylate cyclase activity. Involved in axon midline choice point recognition; retinal ganglion cell axon guidance; and sensory perception of sound. Predicted to localize to integral component of plasma membrane. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 44. Orthologous to human ADCY1 (adenylate cyclase 1).
- Genome Resources
- Note
- None
- Comparative Information
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Santos-Cortez et al., 2014
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
---|---|---|---|
autosomal recessive nonsyndromic deafness 44 | Alliance | ?Deafness, autosomal recessive 44 | 610154 |
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Conserved_site | IPR018297 | Adenylyl cyclase class-4/guanylyl cyclase, conserved site |
Domain | IPR001054 | Adenylyl cyclase class-3/4/guanylyl cyclase |
Domain | IPR009398 | Adenylate cyclase, conserved domain |
Domain | IPR032628 | Adenylate cyclase, N-terminal |
Family | IPR030672 | Adenylate cyclase |
Homologous_superfamily | IPR029787 | Nucleotide cyclase |
Domain Details Per Protein
Protein | Length | Adenylate cyclase | Adenylate cyclase, conserved domain | Adenylate cyclase, N-terminal | Adenylyl cyclase class-3/4/guanylyl cyclase | Adenylyl cyclase class-4/guanylyl cyclase, conserved site | Nucleotide cyclase |
---|---|---|---|---|---|---|---|
UniProtKB:D1MIA3
|
1114 |
Type | Name | Annotation Method | Length (nt) | Analysis |
---|---|---|---|---|
mRNA |
adcy1b-201
(1)
|
Ensembl | 2532 nt | |
mRNA |
adcy1b-202
(1)
|
Havana | 1547 nt |
Interactions and Pathways
No data available
Plasmids
No data available