adcy1b

ID

ZDB-GENE-100805-1

Name

adenylate cyclase 1b

Symbol

adcy1b Nomenclature History

Previous Names

None

Type

protein_coding_gene

Location

Chr: 2 Mapping Details/Browsers

Genome Assembly

GRCz12tu

Annotation Status

Current

Description

Predicted to enable adenylate cyclase activity. Acts upstream of or within axon midline choice point recognition; retinal ganglion cell axon guidance; and sensory perception of sound. Predicted to be located in membrane. Predicted to be active in plasma membrane. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 44. Orthologous to human ADCY1 (adenylate cyclase 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

2 figures from 2 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 1 Figure from Santos-Cortez et al., 2014
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With adcy1b Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
autosomal recessive nonsyndromic deafness 44	Alliance	?Deafness, autosomal recessive 44	610154

Associated With adcy1b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR018297	Adenylyl cyclase class-4/guanylyl cyclase, conserved site
Domain	IPR001054	Adenylyl cyclase class-3/4/guanylyl cyclase
Domain	IPR009398	Adenylate cyclase, conserved domain
Domain	IPR032628	Adenylate cyclase, N-terminal
Family	IPR030672	Adenylate cyclase
Homologous_superfamily	IPR029787	Nucleotide cyclase