Gene
stx1a
- ID
- ZDB-GENE-100802-1
- Name
- syntaxin 1A (brain)
- Symbol
- stx1a Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 15 Mapping Details/Browsers
- Description
- Predicted to enable SNAP receptor activity and SNARE binding activity. Predicted to be involved in intracellular protein transport; synaptic vesicle fusion to presynaptic active zone membrane; and vesicle docking. Predicted to act upstream of or within vesicle-mediated transport. Predicted to be located in synaptic vesicle membrane. Predicted to be part of SNARE complex. Predicted to be active in presynaptic active zone membrane and synaptic vesicle. Human ortholog(s) of this gene implicated in Creutzfeldt-Jakob disease and Hirschsprung's disease. Orthologous to human STX1A (syntaxin 1A).
- Genome Resources
- Note
-
Represented by LOC100006625 and ENSDARG00000058994 on LG15 in Zv8.
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | SNARE | Syntaxin | Syntaxin/epimorphin, conserved site | Syntaxin, N-terminal domain | Target SNARE coiled-coil homology domain |
|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M1PT03 | InterPro | 291 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available