Gene
mrap2a
- ID
- ZDB-GENE-100729-3
- Name
- melanocortin 2 receptor accessory protein 2a
- Symbol
- mrap2a Nomenclature History
- Previous Names
-
- si:ch211-198c19.4
- Type
- protein_coding_gene
- Location
- Chr: 16 Mapping Details/Browsers
- Description
- Enables type 4 melanocortin receptor binding activity. Involved in energy homeostasis and energy reserve metabolic process. Acts upstream of or within several processes, including negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway; protein localization to cell surface; and regulation of growth. Located in Golgi apparatus; endoplasmic reticulum; and plasma membrane. Is expressed in several structures, including adipose tissue; diencephalon; heart; liver; and pleuroperitoneal region. Orthologous to human MRAP2 (melanocortin 2 receptor accessory protein 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 7 figures from 5 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Sebag et al., 2013
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| {?Obesity, susceptibility to, BMIQ18} | 615457 |
1 - 1 of 1
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Family | IPR028111 | Melanocortin-2 receptor accessory protein family |
1 - 1 of 1
Domain Details Per Protein
| Protein | Additional Resources | Length | Melanocortin-2 receptor accessory protein family |
|---|---|---|---|
| UniProtKB:F8W4H9 | InterPro | 217 | |
| UniProtKB:A0AB13ABH2 | InterPro | 217 |
1 - 2 of 2
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
mrap2a-202
(1)
|
Ensembl | 1,950 nt | ||
| ncRNA |
mrap2a-001
(1)
|
Ensembl | 481 nt |
1 - 2 of 2
Interactions and Pathways
No data available
Plasmids
No data available