ZFIN is now using GRCz12tu for Genomic Data
Gene
itgb7
- ID
- ZDB-GENE-100728-2
- Name
- integrin, beta 7
- Symbol
- itgb7 Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 6 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable integrin binding activity. Predicted to be involved in several processes, including cell adhesion mediated by integrin; cell-matrix adhesion; and integrin-mediated signaling pathway. Predicted to act upstream of or within cell adhesion. Predicted to be located in plasma membrane. Predicted to be part of integrin complex. Predicted to be active in cell surface and focal adhesion. Is expressed in inner ear. Orthologous to human ITGB7 (integrin subunit beta 7).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Shi et al., 2019
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR057243 | Integrins beta, I-EGF domain, conserved site |
| Domain | IPR002369 | Integrin beta subunit, VWA domain |
| Domain | IPR014836 | Integrin beta subunit, cytoplasmic domain |
| Domain | IPR016201 | PSI domain |
| Domain | IPR057073 | Integrin beta, epidermal growth factor-like domain 2 |
| Family | IPR015812 | Integrin beta subunit |
| Homologous_superfamily | IPR032695 | Integrin domain superfamily |
| Homologous_superfamily | IPR036465 | von Willebrand factor A-like domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | Integrin beta, epidermal growth factor-like domain 2 | Integrin beta subunit | Integrin beta subunit, cytoplasmic domain | Integrin beta subunit, VWA domain | Integrin domain superfamily | Integrins beta, I-EGF domain, conserved site | PSI domain | von Willebrand factor A-like domain superfamily |
|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M9Q259 | InterPro | 755 | ||||||||
| UniProtKB:A0A8M9PN37 | InterPro | 755 | ||||||||
| UniProtKB:A0A8M9Q931 | InterPro | 755 | ||||||||
| UniProtKB:A0AB32TKK2 | InterPro | 561 | ||||||||
| UniProtKB:A0AC58JVI9 | InterPro | 754 | ||||||||
| UniProtKB:A0AC58JVN7 | InterPro | 755 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers