Gene

il13

ID
ZDB-GENE-100727-2
Name
interleukin 13
Symbol
il13 Nomenclature History
Previous Names
  • IL-4 (1)
  • il4/13a (1)
Type
protein_coding_gene
Location
Chr: 9 Mapping Details/Browsers
Description
Acts upstream of or within cellular response to lipopolysaccharide and negative regulation of inflammatory response. Is expressed in blood; gill; intestine; kidney; and spleen. Human ortholog(s) of this gene implicated in several diseases, including allergic disease (multiple); autoimmune disease (multiple); diffuse scleroderma; lung disease (multiple); and nose disease (multiple). Orthologous to human IL13 (interleukin 13).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
14 figures from 11 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
3 figures from Bottiglione et al., 2020
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Allele Type Localization Consequence Mutagen Supplier
umc17Allele with one insertionUnknownFrameshift, Premature StopCRISPR
1 - 1 of 1
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Sequence Targeting Reagents
Targeting Reagent Created Alleles Citations
CRISPR1-il13
    (2)
    CRISPR2-il13Bottiglione et al., 2020
    1 - 2 of 2
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    Human Disease
    Associated With il13 Human Ortholog
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    allergic rhinitis Alliance {Allergic rhinitis, susceptibility to} 607154
    asthma Alliance {Asthma, susceptibility to} 600807
    1 - 2 of 2
    Associated With il13 Via Experimental Models
    No data available
    Gene Ontology
    Protein Domains
    Domain, Family, and Site Summary
    No data available
    Domain Details Per Protein
    Protein Length
    UniProtKB:B3IWZ9 157
    1 - 1 of 1
    Transcripts
    Genome Browsers
    Genome Build: GRCz11Chromosome: 9
    Type Name Annotation Method Has Havana Data Length (nt) Analysis
    mRNA il13-201 (1) Ensembl 892 nt
    1 - 1 of 1
    Interactions and Pathways
    No data available
    Antibodies
    No data available
    Plasmids
    No data available
    Constructs
    No data available
    Marker Relationships
    Relationship Marker Type Marker Accession Numbers Citations
    Contained inBACCH211-79H18ZFIN Curated Data
    1 - 1 of 1
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    Sequences
    Orthology
    Comparative Orthology
    Alliance
    Gene Tree
    Ensembl
    Species Symbol Chromosome Accession # Evidence
    HumanIL135
    Amino acid sequence comparison (2)
    Phylogenetic tree (1)
    Conserved genome location (synteny) (1)
    MouseIl1311
    Conserved genome location (synteny) (1)
    Amino acid sequence comparison (3)
    Phylogenetic tree (1)
    Citations
    1 - 10 of 49
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