ZFIN is now using GRCz12tu for Genomic Data
Gene
kif26ab
- ID
- ZDB-GENE-100716-6
- Name
- kinesin family member 26Ab
- Symbol
- kif26ab Nomenclature History
- Previous Names
-
- id:ibd5051
- Type
- protein_coding_gene
- Location
- Chr: 17 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable microtubule binding activity. Acts upstream of or within germ cell development. Predicted to be located in cytoplasm and cytoskeleton. Is expressed in several structures, including germ ring; lateral mesoderm; notochord; oocyte; and tail bud. Human ortholog(s) of this gene implicated in complex cortical dysplasia with other brain malformations 11. Orthologous to human KIF26A (kinesin family member 26A).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 6 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Tao et al., 2022
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| complex cortical dysplasia with other brain malformations 11 | Alliance | Cortical dysplasia, complex, with other brain malformations 11 | 620156 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR001752 | Kinesin motor domain |
| Domain | IPR057090 | Kinesin-like protein KIF26A/B, helical domain |
| Family | IPR027640 | Kinesin-like protein |
| Homologous_superfamily | IPR027417 | P-loop containing nucleoside triphosphate hydrolase |
| Homologous_superfamily | IPR036961 | Kinesin motor domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | Kinesin-like protein | Kinesin-like protein KIF26A/B, helical domain | Kinesin motor domain | Kinesin motor domain superfamily | P-loop containing nucleoside triphosphate hydrolase |
|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M2B5F7 | InterPro | 1715 | |||||
| UniProtKB:A0A8M2B5W9 | InterPro | 2023 | |||||
| UniProtKB:A0A8M2B5X7 | InterPro | 2049 | |||||
| UniProtKB:A0A8M2B5I5 | InterPro | 1744 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
kif26ab-201
(1)
|
Ensembl | 8,243 nt | ||
| ncRNA |
kif26ab-002
(1)
|
Ensembl | 777 nt | ||
| ncRNA |
kif26ab-003
(1)
|
Ensembl | 560 nt | ||
| ncRNA |
kif26ab-004
(1)
|
Ensembl | 516 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers
- Comparative Orthology
- Alliance