Gene
nfascb
- ID
- ZDB-GENE-100519-2
- Name
- neurofascin homolog (chicken) b
- Symbol
- nfascb Nomenclature History
- Previous Names
-
- nfasc
- unm_sa43940
- Type
- protein_coding_gene
- Location
- Chr: 23 Mapping Details/Browsers
- Description
- Predicted to enable cell-cell adhesion mediator activity. Acts upstream of or within central nervous system myelin formation. Predicted to be located in membrane. Predicted to be active in axon and plasma membrane. Orthologous to human NFASC (neurofascin).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Klingseisen et al., 2019
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Neurodevelopmental disorder with central and peripheral motor dysfunction | 618356 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR003598 | Immunoglobulin subtype 2 |
| Domain | IPR003599 | Immunoglobulin domain subtype |
| Domain | IPR003961 | Fibronectin type III |
| Domain | IPR007110 | Immunoglobulin-like domain |
| Domain | IPR013098 | Immunoglobulin I-set |
| Domain | IPR026966 | Neurofascin/L1/NrCAM, C-terminal domain |
| Homologous_superfamily | IPR013783 | Immunoglobulin-like fold |
| Homologous_superfamily | IPR036116 | Fibronectin type III superfamily |
| Homologous_superfamily | IPR036179 | Immunoglobulin-like domain superfamily |
Domain Details Per Protein
| Protein | Length | Fibronectin type III | Fibronectin type III superfamily | Immunoglobulin domain subtype | Immunoglobulin I-set | Immunoglobulin-like domain | Immunoglobulin-like domain superfamily | Immunoglobulin-like fold | Immunoglobulin subtype 2 | Neurofascin/L1/NrCAM, C-terminal domain |
|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M9PTE8
|
1162 | |||||||||
|
UniProtKB:A0A4P8NJ80
|
1166 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available