Gene

nrtn

ID

ZDB-GENE-100427-6

Name

neurturin

Symbol

nrtn Nomenclature History

Previous Names

None

Type

protein_coding_gene

Location

Chr: 11 Mapping Details/Browsers

Description

Predicted to have growth factor activity. Predicted to localize to extracellular region. Human ortholog(s) of this gene implicated in Hirschsprung's disease. Orthologous to human NRTN (neurturin).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With nrtn Human Ortholog

No data available

Associated With nrtn Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR001839	Transforming growth factor-beta, C-terminal
Family	IPR043401	Glial cell line-derived neurotrophic factor family
Homologous_superfamily	IPR029034	Cystine-knot cytokine

Domain Details Per Protein

Protein	Length	Cystine-knot cytokine	Glial cell line-derived neurotrophic factor family	Transforming growth factor-beta, C-terminal
UniProtKB:E7FAV4 InterPro	211

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Annotation Method	Has Havana Data	Length (nt)	Analysis
mRNA	nrtn-201 (1) Ensembl	Ensembl		993 nt	Select Tool ZFIN BLAST
mRNA	nrtn-202 (1) Ensembl	Ensembl		2,348 nt	Select Tool

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations