Gene
washc4
- ID
- ZDB-GENE-100427-4
- Name
- WASH complex subunit 4
- Symbol
- washc4 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 25 Mapping Details/Browsers
- Description
- Acts upstream of or within regulation of autophagy. Predicted to be part of WASH complex. Predicted to be active in endosome. Human ortholog(s) of this gene implicated in autosomal recessive intellectual developmental disorder 43. Orthologous to human WASHC4 (WASH complex subunit 4).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Kustermann et al., 2018
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 3 figures from Kustermann et al., 2018
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| autosomal recessive intellectual developmental disorder 43 | Alliance | Intellectual developmental disorder, autosomal recessive 43 | 615817 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | WASH complex subunit 4, N-terminal | WASH complex subunit 7 | WASH complex subunit 7, central domain | WASH complex subunit 7, C-terminal |
|---|---|---|---|---|---|
|
UniProtKB:E7F4L4
|
1173 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
washc4-201
(1)
|
Ensembl | 5,366 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Comparative Orthology
- Alliance