ZFIN is now using GRCz12tu for Genomic Data
Gene
adrb2a
- ID
- ZDB-GENE-100414-3
- Name
- adrenoceptor beta 2, surface a
- Symbol
- adrb2a Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 14 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable beta2-adrenergic receptor activity and norepinephrine binding activity. Acts upstream of or within pigmentation and regulation of heart rate. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in several structures, including blood; digestive system; musculature system; nervous system; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); disease of metabolism (multiple); kidney failure (multiple); lung disease (multiple); and open-angle glaucoma (multiple). Orthologous to human ADRB2 (adrenoceptor beta 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 11 figures from 6 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Beta-2-adrenoreceptor agonist, reduced response to |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Adrenoceptor family | GPCR, rhodopsin-like, 7TM | G protein-coupled receptor, rhodopsin-like |
|---|---|---|---|---|---|
| UniProtKB:I7GPU6 | InterPro | 405 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
adrb2a-201
(1)
|
Ensembl | 5,042 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers