ZFIN is now using GRCz12tu for Genomic Data
Gene
mark4b
- ID
- ZDB-GENE-100330-2
- Name
- MAP/microtubule affinity-regulating kinase 4b
- Symbol
- mark4b Nomenclature History
- Previous Names
-
- mark4
- si:dkey-31m14.7
- Type
- protein_coding_gene
- Location
- Chr: 15 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable ATP binding activity and protein serine/threonine kinase activity. Predicted to act upstream of or within protein phosphorylation. Predicted to be located in dendrite. Orthologous to human MARK4 (microtubule affinity regulating kinase 4).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Active_site | IPR008271 | Serine/threonine-protein kinase, active site |
| Binding_site | IPR017441 | Protein kinase, ATP binding site |
| Domain | IPR000719 | Protein kinase domain |
| Domain | IPR001772 | Kinase associated domain 1 (KA1) |
| Domain | IPR015940 | Ubiquitin-associated domain |
| Domain | IPR049508 | Serine/threonine-protein kinase MARK 1-4, catalytic domain |
| Homologous_superfamily | IPR009060 | UBA-like superfamily |
| Homologous_superfamily | IPR011009 | Protein kinase-like domain superfamily |
| Homologous_superfamily | IPR028375 | KA1 domain/Ssp2, C-terminal |
Domain Details Per Protein
| Protein | Additional Resources | Length | KA1 domain/Ssp2, C-terminal | Kinase associated domain 1 (KA1) | Protein kinase, ATP binding site | Protein kinase domain | Protein kinase-like domain superfamily | Serine/threonine-protein kinase, active site | Serine/threonine-protein kinase MARK 1-4, catalytic domain | UBA-like superfamily | Ubiquitin-associated domain |
|---|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M3B160 | InterPro | 689 | |||||||||
| UniProtKB:A0A8M2B3S3 | InterPro | 796 | |||||||||
| UniProtKB:A0A8M3AIL5 | InterPro | 654 | |||||||||
| UniProtKB:R4GEN1 | InterPro | 693 | |||||||||
| UniProtKB:A0A8M9PCD9 | InterPro | 661 | |||||||||
| UniProtKB:A0A8M2B3X7 | InterPro | 632 | |||||||||
| UniProtKB:A0A8M6Z0W8 | InterPro | 679 | |||||||||
| UniProtKB:A0A8M3AHI1 | InterPro | 792 | |||||||||
| UniProtKB:A0A8M6YSI3 | InterPro | 780 | |||||||||
| UniProtKB:A0A8M2B3S4 | InterPro | 755 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
mark4-201
(1)
|
Ensembl | 4,169 nt | ||
| mRNA |
mark4b-201
(1)
|
Ensembl | 2,103 nt | ||
| mRNA |
mark4b-203
(1)
|
Ensembl | 342 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers