Gene

map3k8

ID
ZDB-GENE-100316-8
Name
mitogen-activated protein kinase kinase kinase 8
Symbol
map3k8 Nomenclature History
Previous Names
None
Type
protein_coding_gene
Location
Chr: 12 Mapping Details/Browsers
Description
Predicted to have ATP binding activity and MAP kinase kinase kinase activity. Predicted to be involved in protein phosphorylation. Orthologous to human MAP3K8 (mitogen-activated protein kinase kinase kinase 8).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
2 figures from Lai et al., 2021
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With map3k8 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
lung cancer Alliance Lung cancer, somatic 211980
Associated With map3k8 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Active_site IPR008271 Serine/threonine-protein kinase, active site
Domain IPR000719 Protein kinase domain
Family IPR050538 Mitogen-activated protein kinase kinase kinase
Homologous_superfamily IPR011009 Protein kinase-like domain superfamily
Domain Details Per Protein
Protein Length Mitogen-activated protein kinase kinase kinase Protein kinase domain Protein kinase-like domain superfamily Serine/threonine-protein kinase, active site
UniProtKB:A0A8N7T7L4 472
Transcripts
Genome Browsers
Type Name Annotation Method Length (nt) Analysis
mRNA map3k8-201 (1) Havana 1724 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations