Gene
map3k8
- ID
- ZDB-GENE-100316-8
- Name
- mitogen-activated protein kinase kinase kinase 8
- Symbol
- map3k8 Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 12 Mapping Details/Browsers
- Description
- Predicted to have ATP binding activity and MAP kinase kinase kinase activity. Predicted to be involved in protein phosphorylation. Orthologous to human MAP3K8 (mitogen-activated protein kinase kinase kinase 8).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from Lai et al., 2021
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| lung cancer | Alliance | Lung cancer, somatic | 211980 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Mitogen-activated protein kinase kinase kinase | Protein kinase domain | Protein kinase-like domain superfamily | Serine/threonine-protein kinase, active site |
|---|---|---|---|---|---|
|
UniProtKB:A0A8N7T7L4
|
472 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
map3k8-201
(1)
|
Ensembl | 1,724 nt |
Interactions and Pathways
No data available
Plasmids
No data available