Gene
afap1
- ID
- ZDB-GENE-100316-6
- Name
- actin filament associated protein 1
- Symbol
- afap1 Nomenclature History
- Previous Names
-
- im:7148276
- Type
- protein_coding_gene
- Location
- Chr: 12 Mapping Details/Browsers
- Description
- Predicted to be involved in regulation of signal transduction. Predicted to be located in cytoplasm. Predicted to be active in actin filament and cytosol. Is expressed in brain. Human ortholog(s) of this gene implicated in open-angle glaucoma. Orthologous to human AFAP1 (actin filament associated protein 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 6 figures from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7148276 (6 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Actin-filament associated protein | PH-like domain superfamily | Pleckstrin homology domain |
|---|---|---|---|---|---|
| UniProtKB:A0A8M9PMC5 | InterPro | 810 | |||
| UniProtKB:A0A8M9PTH1 | InterPro | 806 | |||
| UniProtKB:U3JAR6 | InterPro | 806 | |||
| UniProtKB:A0A8M9Q3X7 | InterPro | 735 | |||
| UniProtKB:A0A8M2B287 | InterPro | 735 | |||
| UniProtKB:A0A8M2B299 | InterPro | 810 |
Interactions and Pathways
No data available
Plasmids
No data available