Gene
grin2cb
- ID
- ZDB-GENE-100308-2
- Name
- glutamate receptor, ionotropic, N-methyl D-aspartate 2Cb
- Symbol
- grin2cb Nomenclature History
- Previous Names
-
- NR2C.2 (1)
- Type
- protein_coding_gene
- Location
- Chr: 12 Mapping Details/Browsers
- Description
- Predicted to have NMDA glutamate receptor activity and transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential. Predicted to be involved in excitatory postsynaptic potential; glutamatergic synaptic transmission; and long-term synaptic potentiation. Predicted to localize to NMDA selective glutamate receptor complex and postsynaptic density membrane. Is expressed in brain. Orthologous to human GRIN2C (glutamate ionotropic receptor NMDA type subunit 2C).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Xie et al., 2017
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR001320 | Ionotropic glutamate receptor, C-terminal |
| Domain | IPR001828 | Receptor, ligand binding region |
| Domain | IPR018884 | Glutamate [NMDA] receptor, epsilon subunit, C-terminal |
| Domain | IPR019594 | Ionotropic glutamate receptor, L-glutamate and glycine-binding domain |
| Family | IPR001508 | Ionotropic glutamate receptor, metazoa |
| Family | IPR015683 | Ionotropic glutamate receptor |
| Homologous_superfamily | IPR028082 | Periplasmic binding protein-like I |
Domain Details Per Protein
| Protein | Length | Glutamate [NMDA] receptor, epsilon subunit, C-terminal | Ionotropic glutamate receptor | Ionotropic glutamate receptor, C-terminal | Ionotropic glutamate receptor, L-glutamate and glycine-binding domain | Ionotropic glutamate receptor, metazoa | Periplasmic binding protein-like I | Receptor, ligand binding region |
|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M3B7K5
|
1328 | |||||||
|
UniProtKB:E7FGL8
|
1328 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
grin2cb-201
(1)
|
Ensembl | 3,987 nt | ||
| mRNA |
grin2cb-202
(1)
|
Ensembl | 4,940 nt |
Interactions and Pathways
No data available
Plasmids
No data available