ZFIN is now using GRCz12tu for Genomic Data
Gene
otud7a
- ID
- ZDB-GENE-100212-1
- Name
- OTU deubiquitinase 7A
- Symbol
- otud7a Nomenclature History
- Previous Names
-
- si:dkey-37f18.2
- Type
- protein_coding_gene
- Location
- Chr: 25 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable K63-linked polyubiquitin modification-dependent protein binding activity and cysteine-type deubiquitinase activity. Predicted to be involved in protein deubiquitination involved in ubiquitin-dependent protein catabolic process. Predicted to be active in cytoplasm and nucleus. Orthologous to human OTUD7A (OTU deubiquitinase 7A).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Neurodevelopmental disorder with hypotonia and seizures | 620790 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | OTU domain | OTU Domain-Containing Deubiquitinase | UBA-like domain | Zinc finger, A20-type |
|---|---|---|---|---|---|---|
| UniProtKB:X1WEZ5 | InterPro | 943 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
otud7a-201
(1)
|
Ensembl | 3,043 nt | ||
| mRNA |
otud7a-202
(1)
|
Ensembl | 2,610 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers
- Comparative Orthology
- Alliance