Gene
usp18
- ID
- ZDB-GENE-100210-2
- Name
- ubiquitin specific peptidase 18
- Symbol
- usp18 Nomenclature History
- Previous Names
-
- si:ch73-352p4.3
- Type
- protein_coding_gene
- Location
- Chr: 4 Mapping Details/Browsers
- Description
- Enables ubiquitin-like protein binding activity. Acts upstream of or within cranial skeletal system development. Predicted to be active in cytosol and nucleus. Orthologous to several human genes including USP18 (ubiquitin specific peptidase 18).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Chen et al., 2015
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Pseudo-TORCH syndrome 2 | 617397 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR018200 | Ubiquitin specific protease, conserved site |
| Domain | IPR001394 | Peptidase C19, ubiquitin carboxyl-terminal hydrolase |
| Domain | IPR028889 | Ubiquitin specific protease domain |
| Family | IPR050164 | Ubiquitin carboxyl-terminal hydrolases |
| Homologous_superfamily | IPR038765 | Papain-like cysteine peptidase superfamily |
Domain Details Per Protein
| Protein | Length | Papain-like cysteine peptidase superfamily | Peptidase C19, ubiquitin carboxyl-terminal hydrolase | Ubiquitin carboxyl-terminal hydrolases | Ubiquitin specific protease, conserved site | Ubiquitin specific protease domain |
|---|---|---|---|---|---|---|
|
UniProtKB:E7EYZ1
|
337 |
Interactions and Pathways
No data available
Plasmids
No data available