Gene

mov10a

ID

ZDB-GENE-091230-8

Name

Mov10 RNA helicase a

Symbol

mov10a Nomenclature History

Previous Names

None

Type

protein_coding_gene

Location

Chr: 6 Mapping Details/Browsers

Description

Predicted to have RNA binding activity. Predicted to be involved in posttranscriptional gene silencing by RNA. Predicted to localize to P granule and cytosol. Human ortholog(s) of this gene implicated in hypertension. Orthologous to human MOV10 (Mov10 RISC complex RNA helicase).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

2 figures from Yang et al., 2022

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With mov10a Human Ortholog

No data available

Associated With mov10a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR026122	Helicase MOV-10/SDE3, DEXXQ/H-box helicase domain
Domain	IPR041677	DNA2/NAM7 helicase, helicase domain
Domain	IPR041679	DNA2/NAM7 helicase-like, C-terminal
Domain	IPR047187	Upf1-like, C-terminal helicase domain
Domain	IPR049075	Helicase MOV-10, N-terminal
Domain	IPR049077	Helicase MOV-10, Ig-like domain
Domain	IPR049079	Helicase MOV-10, helical domain
Domain	IPR049080	Helicase MOV-10-like, beta-barrel domain
Family	IPR045055	DNA2/NAM7-like helicase
Homologous_superfamily	IPR027417	P-loop containing nucleoside triphosphate hydrolase

Domain Details Per Protein

Protein	Length	DNA2/NAM7 helicase, helicase domain	DNA2/NAM7 helicase-like, C-terminal	DNA2/NAM7-like helicase	Helicase MOV-10, helical domain	Helicase MOV-10, Ig-like domain	Helicase MOV-10-like, beta-barrel domain	Helicase MOV-10, N-terminal	Helicase MOV-10/SDE3, DEXXQ/H-box helicase domain	P-loop containing nucleoside triphosphate hydrolase	Upf1-like, C-terminal helicase domain
UniProtKB:E7FAV9 InterPro	1001

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Annotation Method	Has Havana Data	Length (nt)	Analysis
mRNA	mov10a-201 (1) Ensembl	Ensembl		3,377 nt	Select Tool
ncRNA	mov10a-002 (1) Ensembl	Ensembl		652 nt	Select Tool

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations