Gene
tpbg
- ID
- ZDB-GENE-091218-2
- Name
- trophoblast glycoprotein
- Symbol
- tpbg Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 16 Mapping Details/Browsers
- Description
- Predicted to be involved in negative regulation of canonical Wnt signaling pathway. Predicted to be active in plasma membrane. Is expressed in several structures, including head mesenchyme; median fin fold; nervous system; notochord; and otic vesicle. Orthologous to human TPBG (trophoblast glycoprotein).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 12 figures from Thisse et al., 2008
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cssl:d0347 (20 images)
- cssl:d0323 (16 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000372 | Leucine-rich repeat N-terminal domain |
| Domain | IPR000483 | Cysteine-rich flanking region, C-terminal |
| Family | IPR052286 | Wnt/beta-catenin signaling inhibitor |
| Homologous_superfamily | IPR032675 | Leucine-rich repeat domain superfamily |
| Repeat | IPR001611 | Leucine-rich repeat |
| Repeat | IPR003591 | Leucine-rich repeat, typical subtype |
Domain Details Per Protein
| Protein | Additional Resources | Length | Cysteine-rich flanking region, C-terminal | Leucine-rich repeat | Leucine-rich repeat domain superfamily | Leucine-rich repeat N-terminal domain | Leucine-rich repeat, typical subtype | Wnt/beta-catenin signaling inhibitor |
|---|---|---|---|---|---|---|---|---|
| UniProtKB:F1Q983 | InterPro | 382 |
Interactions and Pathways
No data available
Plasmids
No data available