smc1b

ID

ZDB-GENE-091217-1

Name

structural maintenance of chromosomes 1B

Symbol

smc1b Nomenclature History

Previous Names

zmp:0000000547 (1)

Type

protein_coding_gene

Location

Chr: 25 Mapping Details/Browsers

Genome Assembly

GRCz12tu

Annotation Status

Current

Description

Predicted to enable ATP binding activity and ATP hydrolysis activity. Acts upstream of or within several processes, including meiotic telomere clustering; regulation of meiosis I; and spermatogenesis. Predicted to be located in chromosome. Predicted to be part of cohesin complex. Is expressed in gonad. Orthologous to human SMC1B (structural maintenance of chromosomes 1B).

Genome Resources

Note

Represented by LOC797354 and ENSDARG00000014402 on LG25 in Zv8.

Comparative Information

Expression

All Expression Data

3 figures from 3 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 9 figures from Islam et al., 2021
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With smc1b Human Ortholog

No data available

Associated With smc1b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR003395	RecF/RecN/SMC, N-terminal
Domain	IPR010935	SMCs flexible hinge
Domain	IPR028468	Smc1, ATP-binding cassette domain
Family	IPR024704	Structural maintenance of chromosomes protein
Homologous_superfamily	IPR027417	P-loop containing nucleoside triphosphate hydrolase
Homologous_superfamily	IPR036277	SMCs flexible hinge superfamily