Gene
trib2
- ID
- ZDB-GENE-091207-3
- Name
- tribbles pseudokinase 2
- Symbol
- trib2 Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 20 Mapping Details/Browsers
- Description
- Predicted to enable ATP binding activity; protein kinase activity; and protein kinase inhibitor activity. Predicted to act upstream of or within protein phosphorylation. Predicted to be located in cytoskeleton. Orthologous to human TRIB2 (tribbles pseudokinase 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Protein kinase domain | Protein kinase-like domain superfamily | Pseudokinase tribbles family/serine-threonine-protein kinase 40 |
|---|---|---|---|---|---|
| UniProtKB:A0A8M1RLI9 | InterPro | 343 |
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- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549
- Anuppalle, M., Maddirevula, S., Huh, T.L., and Rhee, M. (2013) Trb3 Regulates LR Axis formation in zebrafish embryos. Molecules and cells. 36(6):542-547
- Nishiwaki, Y., Yoshizawa, A., Kojima, Y., Oguri, E., Nakamura, S., Suzuki, S., Yuasa-Kawada, J., Kinoshita-Kawada, M., Mochizuki, T., and Masai, I. (2013) The BH3-Only SNARE BNip1 Mediates Photoreceptor Apoptosis in Response to Vesicular Fusion Defects. Developmental Cell. 25(4):374-387
- Hegedus, Z., Czibula, A., and Kiss-Toth, E. (2007) Tribbles: a family of kinase-like proteins with potent signalling regulatory function. Cellular Signalling. 19(2):238-250
- Hegedus, Z., Czibula, A., and Kiss-Toth, E. (2006) Tribbles: novel regulators of cell function; evolutionary aspects. Cellular and molecular life sciences : CMLS. 63(14):1632-1641
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