ZFIN is now using GRCz12tu for Genomic Data
Gene
fyb1b
- ID
- ZDB-GENE-091204-85
- Name
- FYN binding protein 1 b
- Symbol
- fyb1b Nomenclature History
- Previous Names
-
- fybb (1)
- si:ch211-147j13.3
- Type
- protein_coding_gene
- Location
- Chr: 21 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to be involved in T cell receptor signaling pathway; integrin-mediated signaling pathway; and protein localization to plasma membrane. Predicted to be active in plasma membrane. Human ortholog(s) of this gene implicated in thrombocytopenia. Orthologous to human FYB1 (FYN binding protein 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| thrombocytopenia | Alliance | Thrombocytopenia 3 | 273900 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | FYN-binding protein 1/2-like | Helically-extended SH3 domain | SH3 domain | SH3-like domain superfamily |
|---|---|---|---|---|---|---|
| UniProtKB:A0A8M3AWV8 | InterPro | 736 | ||||
| UniProtKB:A0A8M1QKX1 | InterPro | 723 | ||||
| UniProtKB:A0A8M3ATW5 | InterPro | 705 | ||||
| UniProtKB:A0AB32TF67 | InterPro | 711 | ||||
| UniProtKB:A0AB32TFE0 | InterPro | 742 | ||||
| UniProtKB:A0AB32TGW9 | InterPro | 729 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers
- Comparative Orthology
- Alliance