ZFIN is now using GRCz12tu for Genomic Data
Gene
sftpba
- ID
- ZDB-GENE-091204-378
- Name
- surfactant protein Ba
- Symbol
- sftpba Nomenclature History
- Previous Names
-
- si:ch73-340n8.2
- Type
- protein_coding_gene
- Location
- Chr: 10 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to act upstream of or within sphingolipid metabolic process. Predicted to be located in extracellular region and lysosome. Human ortholog(s) of this gene implicated in lung disease (multiple); respiratory syncytial virus infectious disease; and toxic shock syndrome. Orthologous to human SFTPB (surfactant protein B).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| pulmonary alveolar proteinosis | Alliance | Surfactant metabolism dysfunction, pulmonary, 1 | 265120 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Saposin A-type domain | Saposin B type domain | Saposin B type, region 2 | Saposin-like | Sphingolipid Activators and Surfactant Proteins |
|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M1PYU4 | InterPro | 221 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
sftpba-201
(1)
|
Ensembl | 1,451 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers