Gene
gabra3
- ID
- ZDB-GENE-091204-365
- Name
- gamma-aminobutyric acid type A receptor subunit alpha3
- Symbol
- gabra3 Nomenclature History
- Previous Names
-
- si:ch211-113k9.1
- Type
- protein_coding_gene
- Location
- Chr: 21 Mapping Details/Browsers
- Description
- Predicted to contribute to GABA-A receptor activity; benzodiazepine receptor activity; and chloride channel activity. Predicted to be involved in several processes, including GABAergic synaptic transmission; chloride transmembrane transport; and gamma-aminobutyric acid signaling pathway. Predicted to localize to several cellular components, including GABA-A receptor complex; dendrite membrane; and postsynapse. Human ortholog(s) of this gene implicated in bipolar disorder and multiple sclerosis. Is expressed in brain; eye; and spinal cord. Orthologous to human GABRA3 (gamma-aminobutyric acid type A receptor subunit alpha3).
- Genome Resources
- Note
- None
- Comparative Information
- All Expression Data
- 5 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Barnaby et al., 2022
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
---|---|---|---|
Epilepsy, X-linked 2, with or without impaired intellectual development and dysmorphic features | 301091 |
Domain, Family, and Site Summary
No data available
Domain Details Per Protein
Protein | Length |
---|---|
UniProtKB:A0A8M9PV35
|
305 |
UniProtKB:A0A8M9PJD5
|
306 |
Type | Name | Length (nt) | Analysis |
---|---|---|---|
mRNA |
gabra3-201
(1)
|
374 nt |
Interactions and Pathways
No data available
Plasmids
No data available