Gene
bbx
- ID
- ZDB-GENE-091204-306
- Name
- BBX high mobility group box domain containing
- Symbol
- bbx Nomenclature History
- Previous Names
-
- si:ch211-55i2.1
- Type
- protein_coding_gene
- Location
- Chr: 10 Mapping Details/Browsers
- Description
- Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in head and telencephalon.
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR009071 | High mobility group box domain |
| Domain | IPR019102 | HMG box transcription factor BBX, domain of unknown function DUF2028 |
| Domain | IPR049523 | HMG box transcription factor BBX, HMG-box domain |
| Family | IPR052412 | Cell Cycle and Developmental Transcription Regulators |
| Homologous_superfamily | IPR036910 | High mobility group box domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | Cell Cycle and Developmental Transcription Regulators | High mobility group box domain | High mobility group box domain superfamily | HMG box transcription factor BBX, domain of unknown function DUF2028 | HMG box transcription factor BBX, HMG-box domain |
|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M9Q9B2 | InterPro | 835 | |||||
| UniProtKB:A0A8M9QL56 | InterPro | 869 | |||||
| UniProtKB:A0A8M9PSV2 | InterPro | 898 | |||||
| UniProtKB:A0A8M9PYB5 | InterPro | 836 | |||||
| UniProtKB:A0A8M9Q027 | InterPro | 899 | |||||
| UniProtKB:A0A8M9Q3C9 | InterPro | 898 | |||||
| UniProtKB:A0A8M9Q4P7 | InterPro | 806 |
Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | CH73-213L19 | ZFIN Curated Data | |
| Contained in | BAC | CH211-55I2 | ZFIN Curated Data |
1 - 2 of 2
Show
| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:XM_009305468 (1) | 4333 nt | ||
| Genomic | RefSeq:NW_018395290 (1) | 287446 nt | ||
| Polypeptide | UniProtKB:A0A8M9Q027 (1) | 899 aa |
- Diotel, N., Viales, R.R., Armant, O., März, M., Ferg, M., Rastegar, S., Strähle, U. (2015) Comprehensive expression map of transcription regulators in the adult zebrafish telencephalon reveals distinct neurogenic niches. The Journal of comparative neurology. 523(8):1202-21
- Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549
- Chen, T., Zhou, L., Yuan, Y., Fang, Y., Guo, Y., Huang, H., Zhou, Q., Lv, X. (2014) Characterization of Bbx, a member of a novel subfamily of the HMG-box superfamily together with Cic. Development genes and evolution. 224(4-6):261-8
- Huang, H.T., Kathrein, K.L., Barton, A., Gitlin, Z., Huang, Y.H., Ward, T.P., Hofmann, O., Dibiase, A., Song, A., Tyekucheva, S., Hide, W., Zhou, Y., and Zon, L.I. (2013) A network of epigenetic regulators guides developmental haematopoiesis in vivo. Nature cell biology. 15(12):1516-1525
1 - 4 of 4
Show