Gene
mhc2d8.37a2
- ID
- ZDB-GENE-091204-3
- Name
- major histocompatibility complex class II d8.37a2
- Symbol
- mhc2d8.37a2 Nomenclature History
- Previous Names
-
- si:busm1-160c18.6
- si:dz160c18.6
- si:zfos-2070c2.1 (1)
- Type
- protein_coding_gene
- Location
- Chr: 8 Mapping Details/Browsers
- Description
- Predicted to enable MHC class II protein complex binding activity. Predicted to be involved in antigen processing and presentation of exogenous peptide antigen via MHC class II; peptide antigen assembly with MHC class II protein complex; and positive regulation of T cell activation. Predicted to act upstream of or within adaptive immune response and antigen processing and presentation of peptide or polysaccharide antigen via MHC class II. Predicted to be located in membrane. Predicted to be part of MHC class II protein complex.
- Genome Resources
- Note
-
novel protein similar to MHC class II alpha chain
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR003006 | Immunoglobulin/major histocompatibility complex, conserved site |
| Domain | IPR001003 | MHC class II, alpha chain, N-terminal |
| Domain | IPR003597 | Immunoglobulin C1-set |
| Domain | IPR007110 | Immunoglobulin-like domain |
| Family | IPR050160 | Major Histocompatibility Complex/Immunoglobulin |
| Homologous_superfamily | IPR011162 | MHC classes I/II-like antigen recognition protein |
| Homologous_superfamily | IPR013783 | Immunoglobulin-like fold |
| Homologous_superfamily | IPR014745 | MHC class II, alpha/beta chain, N-terminal |
| Homologous_superfamily | IPR036179 | Immunoglobulin-like domain superfamily |
Domain Details Per Protein
| Protein | Length | Immunoglobulin C1-set | Immunoglobulin-like domain | Immunoglobulin-like domain superfamily | Immunoglobulin-like fold | Immunoglobulin/major histocompatibility complex, conserved site | Major Histocompatibility Complex/Immunoglobulin | MHC classes I/II-like antigen recognition protein | MHC class II, alpha/beta chain, N-terminal | MHC class II, alpha chain, N-terminal |
|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:F1R0K2
|
235 | |||||||||
|
UniProtKB:E9QFF8
|
190 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA | si:busm1-160c18.6-001 (1) | Havana | 708 nt | ||
| mRNA |
si:busm1-160c18.6-201
(1)
|
Ensembl | 1,932 nt | ||
| mRNA |
si:busm1-160c18.6-202
(1)
|
Ensembl | 887 nt |
Interactions and Pathways
No data available
Plasmids
No data available