Gene

vegfbb

ID
ZDB-GENE-091204-285
Name
vascular endothelial growth factor Bb
Symbol
vegfbb Nomenclature History
Previous Names
  • si:dkeyp-36h11.4
Type
protein_coding_gene
Location
Chr: 21 Mapping Details/Browsers
Description
Predicted to have chemoattractant activity; growth factor activity; and vascular endothelial growth factor receptor binding activity. Predicted to be involved in several processes, including positive regulation of chemotaxis; positive regulation of endothelial cell proliferation; and transmembrane receptor protein tyrosine kinase signaling pathway. Predicted to localize to extracellular space. Human ortholog(s) of this gene implicated in myocardial infarction and pulmonary hypertension. Orthologous to human VEGFB (vascular endothelial growth factor B).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With vegfbb Human Ortholog
No data available
Associated With vegfbb Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR023581 Platelet-derived growth factor, conserved site
Domain IPR000072 PDGF/VEGF domain
Family IPR050507 Platelet-derived/Vascular endothelial growth factor
Homologous_superfamily IPR029034 Cystine-knot cytokine
Domain Details Per Protein
Protein Length Cystine-knot cytokine PDGF/VEGF domain Platelet-derived growth factor, conserved site Platelet-derived/Vascular endothelial growth factor
UniProtKB:E9QDL3 91
UniProtKB:A0A8M1RTE1 152
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA vegfbb-201 (1) Ensembl 485 nt
mRNA vegfbb-202 (1) Ensembl 276 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations