Gene

map3k15

ID
ZDB-GENE-091204-246
Name
mitogen-activated protein kinase kinase kinase 15
Symbol
map3k15 Nomenclature History
Previous Names
  • si:dkey-108d10.2
Type
protein_coding_gene
Location
Chr: 24 Mapping Details/Browsers
Description
Predicted to enable MAP kinase kinase kinase activity. Predicted to be involved in JNK cascade and p38MAPK cascade. Predicted to act upstream of or within MAPK cascade and protein phosphorylation. Is expressed in pancreatic D cell; posterior pancreatic bud; and pronephric glomerulus. Orthologous to human MAP3K15 (mitogen-activated protein kinase kinase kinase 15).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
3 figures from Tarifeño-Saldivia et al., 2017
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With map3k15 Human Ortholog
No data available
Associated With map3k15 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Active_site IPR008271 Serine/threonine-protein kinase, active site
Binding_site IPR017441 Protein kinase, ATP binding site
Domain IPR000719 Protein kinase domain
Domain IPR025136 MAP3K, TRAFs-binding domain
Domain IPR043969 MAP3K, PH domain
1 - 5 of 9 Show all
Domain Details Per Protein
Protein Additional Resources Length MAP3K, deoxyribohydrolase domain MAP3K, HisK-N-like globin domain MAP3K, PH domain MAP3K, TRAFs-binding domain Protein kinase, ATP binding site Protein kinase domain Protein kinase-like domain superfamily Serine/threonine-protein kinase, active site Sterile alpha motif/pointed domain superfamily
UniProtKB:A0A8M9PX79 InterPro 1358
UniProtKB:A0A8M9PR29 InterPro 1303
UniProtKB:A0A8M9Q877 InterPro 1335
UniProtKB:A0A8M9PEA4 InterPro 1361
UniProtKB:A0A8M9PEA8 InterPro 1008
1 - 5 of 9 Show all
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA map3k15-201 (1)
Ensembl
Ensembl 6,943 nt
ZFIN BLAST
mRNA map3k15-202 (1)
Ensembl
Ensembl 4,658 nt
ZFIN BLAST
mRNA map3k15-203 (1)
Ensembl
Ensembl 4,047 nt
ZFIN BLAST
1 - 3 of 3
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations
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