Gene
plcxd2
- ID
- ZDB-GENE-091204-217
- Name
- phosphatidylinositol-specific phospholipase C, X domain containing 2
- Symbol
- plcxd2 Nomenclature History
- Previous Names
-
- si:dkey-11p10.9
- Type
- protein_coding_gene
- Location
- Chr: 24 Mapping Details/Browsers
- Description
- Predicted to enable phosphoric diester hydrolase activity. Predicted to act upstream of or within lipid metabolic process. Located in cytoplasm. Orthologous to human PLCXD2 (phosphatidylinositol specific phospholipase C X domain containing 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Choksi et al., 2014
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 2 figures from Choksi et al., 2014
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
| Allele | Type | Localization | Consequence | Mutagen | Supplier |
|---|---|---|---|---|---|
| sa6771 | Allele with one point mutation | Unknown | Premature Stop | ENU |
1 - 1 of 1
Show
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000909 | Phosphatidylinositol-specific phospholipase C, X domain |
| Family | IPR042158 | PI-PLC X domain-containing protein 1/2/3 |
| Family | IPR051057 | Phosphoinositide phospholipase C domain-containing protein |
| Homologous_superfamily | IPR017946 | PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily |
1 - 4 of 4
Domain Details Per Protein
| Protein | Length | Phosphatidylinositol-specific phospholipase C, X domain | Phosphoinositide phospholipase C domain-containing protein | PI-PLC X domain-containing protein 1/2/3 | PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily |
|---|---|---|---|---|---|
|
UniProtKB:A0A8N7UQW3
|
320 |
1 - 1 of 1
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
plcxd2-201
(1)
|
Ensembl | 1,375 nt | ||
| mRNA |
plcxd2-202
(1)
|
Ensembl | 1,036 nt |
1 - 2 of 2
Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | DKEY-11P10 | ZFIN Curated Data |
1 - 1 of 1
Show
| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:XM_683331 (1) | |||
| Genomic | GenBank:CR383672 (1) | 231583 nt | ||
| Polypeptide | UniProtKB:A0A8N7UQW3 (1) | 320 aa |
- Comparative Orthology
- Alliance
- Zhang, J., Chandrasekaran, G., Li, W., Kim, D.Y., Jeong, I.Y., Lee, S.H., Liang, T., Bae, J.Y., Choi, I., Kang, H., Maeng, J.S., Kim, M.K., Lee, T., Park, S.W., Kim, M.J., Kim, H.S., Ro, H., Bae, Y.C., Park, H.C., Choi, E.Y., Choi, S.Y. (2020) Wnt-PLC-IP3-Connexin-Ca2+ axis maintains ependymal motile cilia in zebrafish spinal cord. Nature communications. 11:1860
- Choksi, S.P., Babu, D., Lau, D., Yu, X., Roy, S. (2014) Systematic discovery of novel ciliary genes through functional genomics in the zebrafish. Development (Cambridge, England). 141:3410-9
1 - 2 of 2
Show