si:ch73-74h11.1

ID

ZDB-GENE-091204-215

Name

si:ch73-74h11.1

Symbol

si:ch73-74h11.1 Nomenclature History

Previous Names

None

Type

protein_coding_gene

Location

Chr: 20 Mapping Details/Browsers

Genome Assembly

GRCz12tu

Annotation Status

Current

Description

Predicted to enable calcium ion binding activity. Predicted to be involved in cell-cell adhesion. Predicted to act upstream of or within homophilic cell adhesion via plasma membrane adhesion molecules. Predicted to be located in anchoring junction and plasma membrane. Predicted to be active in desmosome. Human ortholog(s) of this gene implicated in hypotrichosis (multiple); intrinsic cardiomyopathy (multiple); and keratosis palmoplantaris striata 1. Orthologous to several human genes including DSG2 (desmoglein 2).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With si:ch73-74h11.1 Human Ortholog

No data available

Associated With si:ch73-74h11.1 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR020894	Cadherin conserved site
Domain	IPR000233	Cadherin, Y-type LIR-motif
Domain	IPR002126	Cadherin-like
Family	IPR009122	Desmosomal cadherin
Family	IPR050971	Cadherin domain-containing protein
Homologous_superfamily	IPR015919	Cadherin-like superfamily
Homologous_superfamily	IPR027397	Catenin binding domain superfamily