Gene
ltn1
- ID
- ZDB-GENE-091204-127
- Name
- listerin E3 ubiquitin protein ligase 1
- Symbol
- ltn1 Nomenclature History
- Previous Names
-
- si:dkey-175g6.5
- Type
- protein_coding_gene
- Location
- Chr: 10 Mapping Details/Browsers
- Description
- Predicted to enable ribosomal large subunit binding activity and ubiquitin protein ligase activity. Predicted to be involved in rescue of stalled ribosome and ribosome-associated ubiquitin-dependent protein catabolic process. Predicted to be located in cytoplasm. Predicted to be part of RQC complex. Predicted to be active in cytosol. Orthologous to human LTN1 (listerin E3 ubiquitin protein ligase 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR001841 | Zinc finger, RING-type |
| Domain | IPR011016 | Zinc finger, RING-CH-type |
| Domain | IPR039804 | Listerin, zinc finger, RING-type |
| Domain | IPR054476 | E3 ubiquitin-protein ligase listerin, N-terminal domain |
| Domain | IPR054477 | E3 ubiquitin-protein ligase listerin, HEAT repeat region |
| Domain | IPR054478 | E3 ubiquitin-protein ligase listerin, ubiquitin conjugating domain |
| Family | IPR039795 | E3 ubiquitin-protein ligase listerin |
| Homologous_superfamily | IPR011989 | Armadillo-like helical |
| Homologous_superfamily | IPR013083 | Zinc finger, RING/FYVE/PHD-type |
| Homologous_superfamily | IPR016024 | Armadillo-type fold |
Domain Details Per Protein
| Protein | Additional Resources | Length | Armadillo-like helical | Armadillo-type fold | E3 ubiquitin-protein ligase listerin | E3 ubiquitin-protein ligase listerin, HEAT repeat region | E3 ubiquitin-protein ligase listerin, N-terminal domain | E3 ubiquitin-protein ligase listerin, ubiquitin conjugating domain | Listerin, zinc finger, RING-type | Zinc finger, RING-CH-type | Zinc finger, RING/FYVE/PHD-type | Zinc finger, RING-type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:E7F4K2 | InterPro | 1751 |
Interactions and Pathways
No data available
Plasmids
No data available
- Comparative Orthology
- Alliance