Gene
glis2b
- ID
- ZDB-GENE-091204-120
- Name
- GLIS family zinc finger 2b
- Symbol
- glis2b Nomenclature History
- Previous Names
-
- si:rp71-84k24.2
- znphp7.2 (1)
- Type
- protein_coding_gene
- Location
- Chr: 3 Mapping Details/Browsers
- Description
- Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within cilium movement and morphogenesis of an epithelium. Predicted to be located in cytoplasm and nuclear speck. Predicted to be active in nucleus. Is expressed in eye; gut; heart; muscle; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in nephronophthisis 7. Orthologous to human GLIS2 (GLIS family zinc finger 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Kim et al., 2013
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 14 figures from 2 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| nephronophthisis 7 | Alliance | Nephronophthisis 7 | 611498 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | C2H2-type zinc-finger protein GLI-like | ZIC1-5/GLI1-3like, C2H2 zinc finger | Zinc finger C2H2 superfamily | Zinc finger C2H2-type |
|---|---|---|---|---|---|---|
| UniProtKB:T1WQU8 | InterPro | 489 | ||||
| UniProtKB:A0A0R4IE83 | InterPro | 489 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
glis2b-201
(1)
|
Ensembl | 1,470 nt | ||
| mRNA |
glis2b-202
(1)
|
Ensembl | 1,011 nt |
Interactions and Pathways
No data available
Plasmids
No data available