Gene
glis2b
- ID
- ZDB-GENE-091204-120
- Name
- GLIS family zinc finger 2b
- Symbol
- glis2b Nomenclature History
- Previous Names
-
- si:rp71-84k24.2
- znphp7.2 (1)
- Type
- protein_coding_gene
- Location
- Chr: 3 Mapping Details/Browsers
- Description
- Predicted to have DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in cilium movement; left/right pattern formation; and morphogenesis of an epithelium. Predicted to localize to nucleus. Is expressed in eye; gut; heart; muscle; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in nephronophthisis 7. Orthologous to human GLIS2 (GLIS family zinc finger 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Kim et al., 2013
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
Wild Type Expression Summary
- All Phenotype Data
- 14 figures from 2 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| nephronophthisis 7 | Alliance | Nephronophthisis 7 | 611498 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Zinc finger C2H2 superfamily | Zinc finger C2H2-type | Zinc finger protein GLIS2 |
|---|---|---|---|---|
|
UniProtKB:T1WQU8
|
489 | |||
|
UniProtKB:A0A0R4IE83
|
489 | |||
|
UniProtKB:A0A0R4IM25
|
332 |
| Type | Name | Length (nt) | Analysis |
|---|---|---|---|
| mRNA |
glis2b-202
(1)
|
1011 nt |
Interactions and Pathways
No data available
Plasmids
No data available