Gene

glis2b

ID
ZDB-GENE-091204-120
Name
GLIS family zinc finger 2b
Symbol
glis2b Nomenclature History
Previous Names
  • si:rp71-84k24.2
  • znphp7.2 (1)
Type
protein_coding_gene
Location
Chr: 3 Mapping Details/Browsers
Description
Predicted to have DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in cilium movement; left/right pattern formation; and morphogenesis of an epithelium. Predicted to localize to nucleus. Is expressed in eye; gut; heart; muscle; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in nephronophthisis 7. Orthologous to human GLIS2 (GLIS family zinc finger 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Kim et al., 2013
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
14 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With glis2b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
nephronophthisis 7 Alliance Nephronophthisis 7 611498
Associated With glis2b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR013087 Zinc finger C2H2-type
Family IPR030432 Zinc finger protein GLIS2
Homologous_superfamily IPR036236 Zinc finger C2H2 superfamily
Domain Details Per Protein
Protein Length Zinc finger C2H2 superfamily Zinc finger C2H2-type Zinc finger protein GLIS2
UniProtKB:T1WQU8 489
UniProtKB:A0A0R4IE83 489
UniProtKB:A0A0R4IM25 332
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations