ZFIN is now using GRCz12tu for Genomic Data
Gene
pou6f2
- ID
- ZDB-GENE-091118-71
- Name
- POU class 6 homeobox 2
- Symbol
- pou6f2 Nomenclature History
- Previous Names
-
- si:ch211-124o16.3
- Type
- protein_coding_gene
- Location
- Chr: 24 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Enables sequence-specific DNA binding activity. Acts upstream of or within regeneration. Predicted to be located in nucleus. Predicted to be part of RNA polymerase II transcription regulator complex. Human ortholog(s) of this gene implicated in nephroblastoma. Orthologous to human POU6F2 (POU class 6 homeobox 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from Powell et al., 2014
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| {Wilms tumor susceptibility-5} | 601583 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000327 | POU-specific domain |
| Domain | IPR001356 | Homeodomain |
| Domain | IPR013847 | POU domain |
| Family | IPR050255 | POU domain transcription factor |
| Homologous_superfamily | IPR009057 | Homedomain-like superfamily |
| Homologous_superfamily | IPR010982 | Lambda repressor-like, DNA-binding domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | Homedomain-like superfamily | Homeodomain | Lambda repressor-like, DNA-binding domain superfamily | POU domain | POU domain transcription factor | POU-specific domain |
|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A0R4J6S2 | InterPro | 694 | ||||||
| UniProtKB:A0A8M9PGB2 | InterPro | 719 | ||||||
| UniProtKB:A0AB32TCZ8 | InterPro | 658 | ||||||
| UniProtKB:A0AC58ITX8 | InterPro | 694 | ||||||
| UniProtKB:A0AC58ITX9 | InterPro | 719 | ||||||
| UniProtKB:A0AC58ITY0 | InterPro | 694 | ||||||
| UniProtKB:A0AC58ITY1 | InterPro | 683 | ||||||
| UniProtKB:A0AC58ITY2 | InterPro | 683 | ||||||
| UniProtKB:A0AC58ITY3 | InterPro | 719 | ||||||
| UniProtKB:A0AC58ITY5 | InterPro | 683 | ||||||
| UniProtKB:A0AC58ITZ9 | InterPro | 658 | ||||||
| UniProtKB:A0AC58IU03 | InterPro | 658 | ||||||
| UniProtKB:A0AC58IU04 | InterPro | 658 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
pou6f2-201
(1)
|
Ensembl | 710 nt | ||
| mRNA |
pou6f2-203
(1)
|
Ensembl | 4,198 nt | ||
| ncRNA |
pou6f2-002
(1)
|
Ensembl | 570 nt | ||
| ncRNA |
pou6f2-003
(1)
|
Ensembl | 809 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers