Gene
itga2.2
- ID
- ZDB-GENE-091118-70
- Name
- integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor), tandem duplicate 2
- Symbol
- itga2.2 Nomenclature History
- Previous Names
-
- CD49b (1)
- si:dkey-27b3.9
- Type
- protein_coding_gene
- Location
- Chr: 10 Mapping Details/Browsers
- Description
- Predicted to be involved in cell adhesion and integrin-mediated signaling pathway. Predicted to localize to integrin complex. Human ortholog(s) of this gene implicated in several diseases, including Behcet's disease; artery disease (multiple); diabetes mellitus (multiple); inherited blood coagulation disease (multiple); and iron deficiency anemia. Orthologous to human ITGA2 (integrin subunit alpha 2).
- Genome Resources
- Note
- None
- Comparative Information
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
No data available
Human Disease
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Conserved_site | IPR018184 | Integrin alpha chain, C-terminal cytoplasmic region, conserved site |
Domain | IPR002035 | von Willebrand factor, type A |
Domain | IPR013649 | Integrin alpha, first immunoglubulin-like domain |
Domain | IPR048285 | Integrin alpha, second immunoglobulin-like domain |
Domain | IPR048286 | Integrin alpha, third immunoglobulin-like domain |
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Domain Details Per Protein
Protein | Length | FG-GAP repeat | Integrin alpha beta-propellor | Integrin alpha chain | Integrin alpha chain, C-terminal cytoplasmic region, conserved site | Integrin alpha, first immunoglubulin-like domain | Integrin alpha, N-terminal | Integrin alpha, second immunoglobulin-like domain | Integrin alpha, third immunoglobulin-like domain | Integrin domain superfamily | von Willebrand factor A-like domain superfamily | von Willebrand factor, type A |
---|---|---|---|---|---|---|---|---|---|---|---|---|
UniProtKB:F1QC06
|
1197 | |||||||||||
UniProtKB:A0A8M9Q352
|
1197 |
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Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
---|---|---|---|---|---|
mRNA |
itga2.2-201
(1)
|
Ensembl | 3,594 nt |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
Relationship | Marker Type | Marker | Accession Numbers | Citations |
---|---|---|---|---|
Contained in | BAC | CH211-102E1 | ZFIN Curated Data | |
Contained in | BAC | DKEY-27B3 | ZFIN Curated Data |
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Show
Type | Accession # | Sequence | Length (nt/aa) | Analysis |
---|---|---|---|---|
RNA | RefSeq:XM_003199304 (1) | 4645 nt | ||
Genomic | GenBank:BX571955 (1) | 272498 nt | ||
Polypeptide | UniProtKB:A0A8M9Q352 (1) | 1197 aa |