ZFIN is now using GRCz12tu for Genomic Data
Gene
gucy2ca
- ID
- ZDB-GENE-091118-67
- Name
- guanylate cyclase 2Ca
- Symbol
- gucy2ca Nomenclature History
- Previous Names
-
- gucy2c
- si:ch211-163m16.1
- Type
- protein_coding_gene
- Location
- Chr: 3 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable guanylate cyclase activity and peptide receptor activity. Predicted to be involved in cGMP biosynthetic process and receptor guanylyl cyclase signaling pathway. Predicted to act upstream of or within cyclic nucleotide biosynthetic process; intracellular signal transduction; and protein phosphorylation. Predicted to be located in endoplasmic reticulum and membrane. Predicted to be active in plasma membrane. Human ortholog(s) of this gene implicated in congenital diarrhea 6. Orthologous to human GUCY2C (guanylate cyclase 2C).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Pérez-Rius et al., 2019
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| congenital diarrhea 6 | Alliance | Diarrhea 6 | 614616 |
| Meconium ileus | 614665 |
Domain, Family, and Site Summary
No data available
Domain Details Per Protein
| Protein | Additional Resources | Length |
|---|---|---|
| UniProtKB:A0A8M3AQ67 | InterPro | 1025 |
| UniProtKB:A0AC58J0C3 | InterPro | 1071 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
gucy2c-201
(1)
|
Ensembl | 3,075 nt | ||
| mRNA |
gucy2c-202
(1)
|
Ensembl | 2,895 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers