Gene

rab34b

ID
ZDB-GENE-091118-61
Name
RAB34, member RAS oncogene family b
Symbol
rab34b Nomenclature History
Previous Names
  • si:dkey-220h13.7
Type
protein_coding_gene
Location
Chr: 21 Mapping Details/Browsers
Description
Predicted to enable GTP binding activity and GTPase activity. Predicted to be involved in Golgi to plasma membrane protein transport and phagosome-lysosome fusion. Predicted to be active in Golgi cisterna and phagocytic vesicle. Human ortholog(s) of this gene implicated in orofaciodigital syndrome XX. Orthologous to human RAB34 (RAB34, member RAS oncogene family).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Allele Type Localization Consequence Mutagen Supplier
sa7306Allele with one point mutationUnknownSplice SiteENU
sa12037Allele with one point mutationUnknownPremature StopENU
European Zebrafish Resource Center (EZRC) (order this)
Zebrafish International Resource Center (ZIRC) (order this)
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Sequence Targeting Reagents
No data available
Human Disease
Associated With rab34b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
orofaciodigital syndrome XX Alliance Orofaciodigital syndrome XX 620718
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Associated With rab34b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR005225 Small GTP-binding domain
Family IPR001806 Small GTPase
Family IPR050227 Ras-related protein Rab
Homologous_superfamily IPR027417 P-loop containing nucleoside triphosphate hydrolase
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Domain Details Per Protein
Protein Additional Resources Length P-loop containing nucleoside triphosphate hydrolase Ras-related protein Rab Small GTPase Small GTP-binding domain
UniProtKB:A0A8M1Q809 InterPro 254
UniProtKB:E7FG87 InterPro 166
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Transcripts
Genome Browsers
Genome Build: GRCz11Chromosome: 21
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA rab34b-201 (1)
Ensembl
Ensembl 1,062 nt
ZFIN BLAST
mRNA rab34b-202 (1)
Ensembl
Ensembl 1,365 nt
ZFIN BLAST
ncRNA rab34b-002 (1)
Ensembl
Ensembl 576 nt
ZFIN BLAST
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Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
Constructs
No data available
Marker Relationships
Relationship Marker Type Marker Accession Numbers Citations
Contained inBACDKEY-220H13ZFIN Curated Data
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Sequences
Type Accession # Sequence Length (nt/aa) Analysis
RNARefSeq:XM_001346037 (1)
ZFIN BLASTNCBI BLASTMegaBLASTEnsemblUCSC BLAT
GenomicGenBank:CR749178 (1)102340 nt
MegaBLASTEnsembl
PolypeptideUniProtKB:A0A8M1Q809 (1)254 aa
ZFIN BLASTSIB BLASTEnsembl Protein Blast
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Species Symbol Chromosome Accession # Evidence
HumanRAB3417
Amino acid sequence comparison (1)
Conserved genome location (synteny) (2)
MouseRab3411
Conserved genome location (synteny) (1)
Amino acid sequence comparison (1)
Citations
TSV
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