mcf2b

ID

ZDB-GENE-091118-4

Name

MCF.2 cell line derived transforming sequence b

Symbol

mcf2b Nomenclature History

Previous Names

si:ch211-263p13.4

Type

protein_coding_gene

Location

Chr: 10 Mapping Details/Browsers

Genome Assembly

GRCz12tu

Annotation Status

Current

Description

Predicted to enable guanyl-nucleotide exchange factor activity. Predicted to be involved in dendrite development. Predicted to act upstream of or within intracellular signal transduction. Predicted to be active in cytoplasm.

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With mcf2b Human Ortholog

No data available

Associated With mcf2b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR001331	Guanine-nucleotide dissociation stimulator, CDC24, conserved site
Domain	IPR000219	Dbl homology domain
Domain	IPR001849	Pleckstrin homology domain
Domain	IPR055251	SOS1/NGEF-like, PH domain
Domain	IPR056466	Guanine nucleotide exchange factor DBS-like, spectrin-like
Domain	IPR058918	Kalirin/TRIO-like, spectrin repeats
Family	IPR051336	Rho GTPase-activating Guanine Nucleotide Exchange Factors
Homologous_superfamily	IPR011993	PH-like domain superfamily
Homologous_superfamily	IPR035899	Dbl homology (DH) domain superfamily
Homologous_superfamily	IPR036028	SH3-like domain superfamily
Repeat	IPR018159	Spectrin/alpha-actinin

Domain Details Per Protein

Protein	Additional Resources	Length
UniProtKB:A0A8M9QCH5	InterPro	1029
UniProtKB:A0A8M9QH11	InterPro	1018
UniProtKB:A0A8M1RM37	InterPro	1027
UniProtKB:A0A8M3AWT4	InterPro	1037
UniProtKB:A0A8M3B396	InterPro	1046
UniProtKB:A0A8M3AWR0	InterPro	1018
UniProtKB:A0A8M3BD02	InterPro	1029
UniProtKB:A0AC58GMG1	InterPro	1030
UniProtKB:A0AC58GMG2	InterPro	999
UniProtKB:A0AC58GMH6	InterPro	1010
UniProtKB:A0AC58GMH7	InterPro	1001
UniProtKB:A0AC58GMH8	InterPro	674
UniProtKB:A0AC58GMH9	InterPro	982
UniProtKB:A0AC58GMI8	InterPro	515
UniProtKB:A0AC58GMJ2	InterPro	534
UniProtKB:A0AC58GML0	InterPro	534