Gene
aak1b
- ID
- ZDB-GENE-091118-25
- Name
- AP2 associated kinase 1b
- Symbol
- aak1b Nomenclature History
- Previous Names
-
- aak1
- si:dkey-261l11.5
- Type
- protein_coding_gene
- Location
- Chr: 10 Mapping Details/Browsers
- Description
- Predicted to have AP-2 adaptor complex binding activity and protein serine/threonine kinase activity. Predicted to be involved in positive regulation of Notch signaling pathway; protein phosphorylation; and regulation of clathrin-dependent endocytosis. Predicted to localize to nucleus. Orthologous to human AAK1 (AP2 associated kinase 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Active_site | IPR008271 | Serine/threonine-protein kinase, active site |
| Domain | IPR000719 | Protein kinase domain |
| Domain | IPR028182 | BMP-2-inducible protein kinase, C-terminal |
| Family | IPR051744 | AP2-associated Ser/Thr protein kinase |
| Homologous_superfamily | IPR011009 | Protein kinase-like domain superfamily |
Domain Details Per Protein
| Protein | Length | AP2-associated Ser/Thr protein kinase | BMP-2-inducible protein kinase, C-terminal | Protein kinase domain | Protein kinase-like domain superfamily | Serine/threonine-protein kinase, active site |
|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M3AX64
|
890 | |||||
|
UniProtKB:A0A8M3BDD0
|
955 | |||||
|
UniProtKB:A0A8M9PUF5
|
1020 | |||||
|
UniProtKB:A0A8M3B6K5
|
1055 | |||||
|
UniProtKB:A0A8M3AX89
|
1054 |
Interactions and Pathways
No data available
Plasmids
No data available