Gene
grb7
- ID
- ZDB-GENE-091118-23
- Name
- growth factor receptor bound protein 7
- Symbol
- grb7 Nomenclature History
- Previous Names
-
- si:ch211-253b1.3 (1)
- Type
- protein_coding_gene
- Location
- Chr: 24 Mapping Details/Browsers
- Description
- Predicted to act upstream of or within signal transduction. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in esophagus adenocarcinoma. Orthologous to human GRB7 (growth factor receptor bound protein 7).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000159 | Ras-associating domain |
| Domain | IPR000980 | SH2 domain |
| Domain | IPR001849 | Pleckstrin homology domain |
| Domain | IPR015042 | BPS (Between PH and SH2) domain |
| Domain | IPR039665 | APBB1IP, PH domain |
| Family | IPR039664 | GRB/APBB1IP |
| Homologous_superfamily | IPR011993 | PH-like domain superfamily |
| Homologous_superfamily | IPR029071 | Ubiquitin-like domain superfamily |
| Homologous_superfamily | IPR036860 | SH2 domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | APBB1IP, PH domain | BPS (Between PH and SH2) domain | GRB/APBB1IP | PH-like domain superfamily | Pleckstrin homology domain | Ras-associating domain | SH2 domain | SH2 domain superfamily | Ubiquitin-like domain superfamily |
|---|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M1RN50 | InterPro | 530 |
Interactions and Pathways
No data available
Plasmids
No data available
- Comparative Orthology
- Alliance