Gene

gfi1b

ID
ZDB-GENE-091118-129
Name
growth factor independent 1B transcription repressor
Symbol
gfi1b Nomenclature History
Previous Names
  • si:ch211-231o6.2
Type
protein_coding_gene
Location
Chr: 21 Mapping Details/Browsers
Description
Predicted to have DNA-binding transcription factor activity; RNA polymerase II regulatory region sequence-specific DNA binding activity; and chromatin DNA binding activity. Involved in definitive hemopoiesis and erythrocyte differentiation. Predicted to localize to nucleus. Human ortholog(s) of this gene implicated in gray platelet syndrome and platelet-type bleeding disorder 17. Is expressed in ectoderm; erythroblast; hematopoietic system; otic vesicle; and posterior lateral mesoderm. Orthologous to human GFI1B (growth factor independent 1B transcriptional repressor).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
5 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
4 figures from 3 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With gfi1b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
platelet-type bleeding disorder 17 Alliance Bleeding disorder, platelet-type, 17 187900
Associated With gfi1b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR013087 Zinc finger C2H2-type
Homologous_superfamily IPR036236 Zinc finger C2H2 superfamily
Domain Details Per Protein
Protein Length Zinc finger C2H2 superfamily Zinc finger C2H2-type
UniProtKB:E7FBX7 334
UniProtKB:F1QP37 237
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations