ZFIN is now using GRCz12tu for Genomic Data
Gene
gfi1b
- ID
- ZDB-GENE-091118-129
- Name
- growth factor independent 1B transcription repressor
- Symbol
- gfi1b Nomenclature History
- Previous Names
-
- si:ch211-231o6.2
- Type
- protein_coding_gene
- Location
- Chr: 21 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable DNA binding activity and zinc ion binding activity. Acts upstream of or within definitive hemopoiesis and erythrocyte differentiation. Predicted to be active in nucleus. Is expressed in ectoderm; erythroblast; hematopoietic system; otic vesicle; and posterior lateral mesoderm. Human ortholog(s) of this gene implicated in gray platelet syndrome and platelet-type bleeding disorder 17. Orthologous to human GFI1B (growth factor independent 1B transcriptional repressor).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 6 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| platelet-type bleeding disorder 17 | Alliance | Bleeding disorder, platelet-type, 17 | 187900 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Zinc finger C2H2 superfamily | Zinc finger C2H2-type |
|---|---|---|---|---|
| UniProtKB:E7FBX7 | InterPro | 334 | ||
| UniProtKB:J9PE59 | InterPro | 334 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers