Gene

gfi1b

ID
ZDB-GENE-091118-129
Name
growth factor independent 1B transcription repressor
Symbol
gfi1b Nomenclature History
Previous Names
  • si:ch211-231o6.2
Type
protein_coding_gene
Location
Chr: 21 Mapping Details/Browsers
Description
Predicted to enable metal ion binding activity. Acts upstream of or within definitive hemopoiesis and erythrocyte differentiation. Predicted to be active in nucleus. Is expressed in ectoderm; erythroblast; hematopoietic system; otic vesicle; and posterior lateral mesoderm. Human ortholog(s) of this gene implicated in gray platelet syndrome and platelet-type bleeding disorder 17. Orthologous to human GFI1B (growth factor independent 1B transcriptional repressor).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
5 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
4 figures from 3 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With gfi1b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
platelet-type bleeding disorder 17 Alliance Bleeding disorder, platelet-type, 17 187900
1 - 1 of 1
Associated With gfi1b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR013087 Zinc finger C2H2-type
Homologous_superfamily IPR036236 Zinc finger C2H2 superfamily
1 - 2 of 2
Domain Details Per Protein
Protein Additional Resources Length Zinc finger C2H2 superfamily Zinc finger C2H2-type
UniProtKB:E7FBX7 InterPro 334
UniProtKB:J9PE59 InterPro 334
1 - 2 of 2
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA gfi1b-201 (1) Ensembl 1,058 nt
mRNA gfi1b-202 (1) Ensembl 754 nt
mRNA gfi1b-203 (1) Ensembl 1,362 nt
1 - 3 of 3
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations